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==Three-dimensional Analysis of Human Pancreatic Islet==
==Three-dimensional Analysis of Human Pancreatic Islet==


Consecutive sections through an entire pancreatic islet labeled for insulin (red) and glucagon (green). Images show that insulin (red)and glucagon (green)–stained cells are organized into continuous 3-D networks that span the entire islet. Sections at both ends show islet profiles with an apparent similar core-mantle structure to that of 40- to 60-μm–diameter islets. These consecutive images also reveal that vascular channels were in fact continuous ramified structures that were connected in places with the surrounding islet tissue (arrowheads). Image series is representative of 15 different pancreatic islets analyzed from one pancreas. Scale bar, 50 μm. (A high-quality digital representation of this figure is available in the online issue.)
* Consecutive sections through an entire adult pancreatic islet labeled for insulin (red) and glucagon (green).  
* Images show that insulin (red) and glucagon (green) stained cells are organized into continuous 3-D networks that span the entire islet.  
* Sections at both ends show islet profiles with an apparent similar core-mantle structure to that of 40- to 60-μm–diameter islets.  
* These consecutive images also reveal that vascular channels were in fact continuous ramified structures that were connected in places with the surrounding islet tissue (arrowheads).  
* Image series is representative of 15 different pancreatic islets analyzed from one pancreas.  
 
Scale bar, 50 μm.


:'''Links:''' [[:File:Human- pancreatic adult islet.jpg|Image - Islet Insulin and Glucagon]] | [[Endocrine - Pancreas Development]]
:'''Links:''' [[:File:Human- pancreatic adult islet.jpg|Image - Islet Insulin and Glucagon]] | [[Endocrine - Pancreas Development]]




Original file name:  FIG. 4. http://diabetes.diabetesjournals.org/content/59/5/1202/F4.large.jpg
Original file name:  FIG. 4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857900/figure/F4/ http://diabetes.diabetesjournals.org/content/59/5/1202/F4.large.jpg
===Reference===
===Reference===
<pubmed>20185817</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857900 PMC2857900] | [http://diabetes.diabetesjournals.org/content/59/5/1202.full Diabetes.]
<pubmed>20185817</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857900 PMC2857900] | [http://diabetes.diabetesjournals.org/content/59/5/1202.full Diabetes.]
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Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.


[[Category:Human]] [[Category:Pancreas]] [[Category:Endocrine]] [[Category:Immunofluorescence]]
[[Category:Human]] [[Category:Pancreas]] [[Category:Endocrine]]

Latest revision as of 13:50, 8 August 2011

Three-dimensional Analysis of Human Pancreatic Islet

  • Consecutive sections through an entire adult pancreatic islet labeled for insulin (red) and glucagon (green).
  • Images show that insulin (red) and glucagon (green) stained cells are organized into continuous 3-D networks that span the entire islet.
  • Sections at both ends show islet profiles with an apparent similar core-mantle structure to that of 40- to 60-μm–diameter islets.
  • These consecutive images also reveal that vascular channels were in fact continuous ramified structures that were connected in places with the surrounding islet tissue (arrowheads).
  • Image series is representative of 15 different pancreatic islets analyzed from one pancreas.

Scale bar, 50 μm.

Links: Image - Islet Insulin and Glucagon | Endocrine - Pancreas Development


Original file name: FIG. 4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857900/figure/F4/ http://diabetes.diabetesjournals.org/content/59/5/1202/F4.large.jpg

Reference

<pubmed>20185817</pubmed>| PMC2857900 | Diabetes.

© 2010 by the American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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current13:43, 8 August 2011Thumbnail for version as of 13:43, 8 August 20111,088 × 1,280 (295 KB)S8600021 (talk | contribs)==Three-dimensional Analysis of Human Pancreatic Islet== Consecutive sections through an entire pancreatic islet labeled for insulin (red) and glucagon (green). Images show that insulin (red)– and glucagon (green)–stained cells are organized into con