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(Diagram of Polar body 1 transfer in in-vitro fertilizatio) |
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Diagram of Polar body 1 transfer in in-vitro | =Diagram of Polar body 1 transfer in in-vitro fertilization= | ||
Polar bodies are small cells formed during the meiotic reductive division of the oocyte. they contains complementary choromosomes (to the mature oocyte) and small amount of cytoplasmic segregation | |||
* The Polar Body 1 of patient's egg is removed for transfer to the donor egg. The leftover egg, which contains the unhealthy mitochondria, is then discarded. | |||
* a donated egg is also extracted from an unrelated woman who has healthy mitochondria. Similarly, the chromosomes of the donor’s egg are removed. However, these chromosomes are discarded, leaving behind the healthy mitochondria in the cytoplasm. | |||
* The Polar body 1 previously taken from the patient's egg are inserted into the enucleated donor’s egg. | |||
*The resulting reconstructed egg contains nuclear DNA from the mother and the healthy mitochondria from the donor. | |||
*The resulting egg can now be fertilized with sperm from the intended father. The resulting embryo will be implanted into the intending mother and will develop unaffected by inherited mitochondrial disease. | |||
=Reference= | |||
<pubmed> 25472922 </pubmed> | |||
=copyright= | |||
Copyright © z3251292. permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||
{{Student Image}} |
Latest revision as of 14:20, 22 October 2015
Diagram of Polar body 1 transfer in in-vitro fertilization
Polar bodies are small cells formed during the meiotic reductive division of the oocyte. they contains complementary choromosomes (to the mature oocyte) and small amount of cytoplasmic segregation
- The Polar Body 1 of patient's egg is removed for transfer to the donor egg. The leftover egg, which contains the unhealthy mitochondria, is then discarded.
- a donated egg is also extracted from an unrelated woman who has healthy mitochondria. Similarly, the chromosomes of the donor’s egg are removed. However, these chromosomes are discarded, leaving behind the healthy mitochondria in the cytoplasm.
- The Polar body 1 previously taken from the patient's egg are inserted into the enucleated donor’s egg.
- The resulting reconstructed egg contains nuclear DNA from the mother and the healthy mitochondria from the donor.
- The resulting egg can now be fertilized with sperm from the intended father. The resulting embryo will be implanted into the intending mother and will develop unaffected by inherited mitochondrial disease.
Reference
<pubmed> 25472922 </pubmed>
copyright
Copyright © z3251292. permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Note - This image was originally uploaded as part of an undergraduate science student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.
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