File:Implantation cartoon 02.jpg: Difference between revisions

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| Key molecules for decidualization are depicted in this hybrid cartoon as gathered from mouse and human studies. The decidua is composed of differentiated stromal (decidual) cells, many of which are terminally differentiated (polyploid).  
| Key molecules for decidualization are depicted in this hybrid cartoon as gathered from mouse and human studies. The decidua is composed of differentiated stromal (decidual) cells, many of which are terminally differentiated (polyploid).  


Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.  
Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.  
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* '''ADM''' - adrenomedullin
* '''ADM''' - adrenomedullin
* '''BV''' - blood vessel
* '''BV''' - blood vessel
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Adrenomedullin - secreted by both decidual and trophoblast cells, angiogenic and natriuretic factor both promoting growth.
:'''Links:''' [[Implantation]] | [[Week 2]]


===Reference===
===Reference===


<pubmed>23223073</pubmed>| [http://www.nature.com/nm/journal/v18/n12/full/nm.3012.html Nat Med]
{{#pmid:23223073}}


====Copyright====
====Copyright====
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Cha J, Sun X, Dey SK. Nat Med. 2012 Dec;18(12):1754-67. doi: 10.1038/nm.3012. Review. PMID 23223073), copyright (2012)
Cha J, Sun X, Dey SK. Nat Med. 2012 Dec;18(12):1754-67. doi: 10.1038/nm.3012. Review. PMID 23223073), copyright (2012)


[[Category:Implantation]] [[Category:Cartoon]]
Nm.3012-F2.jpg


Nm.3012-F2.jpg
{{footer}}
[[Category:Implantation]] [[Category:Molecular]] [[Category:Cartoon]] [[Category:Week 2]]

Latest revision as of 10:58, 29 April 2020

Key Molecules for Decidualization

Legend
Key molecules for decidualization are depicted in this hybrid cartoon as gathered from mouse and human studies. The decidua is composed of differentiated stromal (decidual) cells, many of which are terminally differentiated (polyploid).


Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.

  • ADM - adrenomedullin
  • BV - blood vessel
  • DEDD - death effector domain–containing protein
  • IL-11Rα - interleukin 11 receptor α
  • mTORC1 - mammalian target of rapamycin complex 1
  • SGK1 - serum- and glucocorticoid-inducible kinase 1
  • Sphk1/2 - sphingosine kinase 1/2

Adrenomedullin - secreted by both decidual and trophoblast cells, angiogenic and natriuretic factor both promoting growth.


Links: Implantation | Week 2

Reference

Cha J, Sun X & Dey SK. (2012). Mechanisms of implantation: strategies for successful pregnancy. Nat. Med. , 18, 1754-67. PMID: 23223073 DOI.

Copyright

Reprinted by permission from Macmillan Publishers Ltd: Nature Medicine (Mechanisms of implantation: strategies for successful pregnancy. Cha J, Sun X, Dey SK. Nat Med. 2012 Dec;18(12):1754-67. doi: 10.1038/nm.3012. Review. PMID 23223073), copyright (2012)

Nm.3012-F2.jpg

Cite this page: Hill, M.A. (2026, October 15) Embryology Implantation cartoon 02.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Implantation_cartoon_02.jpg

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© Dr Mark Hill 2026, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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