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Tectum Development Signaling Model

Model for a possible cooperation of Meis2, Pax3, Pax7 and Otx2 during tectal development.

MHB - mid-hindbrain boundary

Red lines indicate negative regulation, green arrows positive regulation. Dashed lines indicate hypothetical direct regulation of the Meis2 promoter/enhancer by different Pax3 concentrations. Solid lines indicate indirect regulation of Meis2 expression via Pax3/7 mediated induction of Fgf8 as previously reported:

Regulation of Meis2 expression in response to Ras-MAPK signaling levels
Induction of Fgf8 by Pax3 and Pax7
Existence of Meis2-Otx2 containing protein complexes in the tectal anlage

Links: tectum

Reference

Agoston Z, Li N, Haslinger A, Wizenmann A & Schulte D. (2012). Genetic and physical interaction of Meis2, Pax3 and Pax7 during dorsal midbrain development. BMC Dev. Biol. , 12, 10. PMID: 22390724 DOI.

Copyright

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Agoston et al. BMC Developmental Biology 2012 12:10 doi:10.1186/1471-213X-12-10

1471-213X-12-10-6.jpg

Cite this page: Hill, M.A. (2026, November 2) Embryology Tectum signaling model 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Tectum_signaling_model_01.jpg

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	Gwalagizhi	Nyangagi	Dimensions	User	Comment
current	08:50, 11 Haziran 2012		600 × 314 (41 KB)	Z8600021 (talk \| contribs)	==Tectum Development Signaling Model== Model for a possible cooperation of Meis2, Pax3, Pax7 and Otx2during tectal development. Red lines indicate negative regulation, green arrows positive regulation. Dashed lines indicate hypothetical direct regulat

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Neural - Tectum Development

@@ Line 1: / Line 1: @@
 ==Tectum Development Signaling Model==
-Model for a possible cooperation of Meis2, Pax3, Pax7 and Otx2during tectal development.
+Model for a possible cooperation of Meis2, {{Pax}}3, {{Pax}}7 and Otx2 during tectal development.
+* MHB - mid-hindbrain boundary
 Red lines indicate negative regulation, green arrows positive regulation. Dashed lines indicate hypothetical direct regulation of the Meis2 promoter/enhancer by different Pax3 concentrations. Solid lines indicate indirect regulation of Meis2 expression via Pax3/7 mediated induction of Fgf8 as previously reported:
-(1) Regulation of Meis2 expression in response to Ras-MAPK signaling levels reported in [19];
+# Regulation of Meis2 expression in response to Ras-MAPK signaling levels
+# Induction of Fgf8 by Pax3 and Pax7
-(2) Induction of Fgf8 by Pax3 and Pax7 reported in [11];
+# Existence of Meis2-Otx2 containing protein complexes in the tectal anlage
-(3) Existence of Meis2-Otx2 containing protein complexes in the tectal anlage reported in [17].
+:'''Links:''' {{tectum}}
 ===Reference===
-<pubmed>22390724</pubmed>| [http://www.biomedcentral.com/1471-213X/12/10 BMC Dev Biol.]
+{{#pmid:22390724}}
+====Copyright====
 © 2012 Agoston et al; licensee BioMed Central Ltd.
@@ Line 24: / Line 24: @@
 -213X-12-10-6.jpg
+{{Footer}}
+[[Category:Chicken]] [[Category:Neural]] [[Category:Vision]]