File:Sheep follicle gene expression 01.jpg: Difference between revisions

Latest revision as of 22:37, 12 November 2015

Sheep Follicle Gene Expression

red - genes expressed in granulose cells.
blue - genes expressed in oocytes.
black - genes expressed both in oocytes and granulosa cells.

Follicle type and diameter

primordial (PD) < 35 μM
primary (PM) 35 – 50 μM
secondary follicles (SC) 60 – 120 μM
small antral follicles (SA) 250 – 500 μM

Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG).

They were selected using pairwise comparisons (nbinom Test) comparing each stage to the others including multi-tissue samples (FDR<5% and a fold change >3 for granulosa samples and a fold change >-10 for oocyte samples). Their differential expression was confirmed by qRT-PCR.

Links: Granulosa cell | Oocyte Development | Sheep Development

Reference

<pubmed>26540452</pubmed>| PLoS One.

Copyright

© 2015 Bonnet et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Bonnet A, Servin B, Mulsant P, Mandon-Pepin B (2015) Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Folliculogenesis: Integrated Transcriptomic Study and Molecular Signature of Early Follicular Growth. PLoS ONE 10(11): e0141482. doi:10.1371/journal.pone.0141482

Fig 9. journal.pone.0141482.g009.jpg

Cite this page: Hill, M.A. (2024, June 25) Embryology Sheep follicle gene expression 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Sheep_follicle_gene_expression_01.jpg

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current	22:11, 12 November 2015		1,235 × 1,000 (168 KB)	Z8600021 (talk \| contribs)	Fig 9. Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG). They were selec...

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-Fig 9. Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG). They were selected using pairwise comparisons (nbinom Test) comparing each stage to the others including multi-tissue samples (FDR<5% and a fold change >3 for granulosa samples and a fold change >-10 for oocyte samples). Their differential expression was confirmed by qRT-PCR. Gene names marked in red are genes expressed in granulosa cells and gene names marked in blue are genes expressed in oocytes. Gene names marked in black are genes expressed both in oocytes and granulosa cells.
+==Sheep Follicle Gene Expression==
+{|
+| width=300px|
+* <font color=red>'''red'''</font> - genes expressed in granulose cells.
+* <font color=blue>'''blue'''</font> - genes expressed in oocytes.
+* '''black''' - genes expressed both in oocytes and granulosa cells.
-PMID--26540452journal.pone.0141482.g009.jpg
+Follicle type and diameter
+* primordial (PD) < 35 μM
+* primary (PM) 35 – 50 μM
+* secondary follicles (SC) 60 – 120 μM
+* small antral follicles (SA) 250 – 500 μM
+| Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG).
+They were selected using pairwise comparisons (nbinom Test) comparing each stage to the others including multi-tissue samples (FDR<5% and a fold change >3 for granulosa samples and a fold change >-10 for oocyte samples). Their differential expression was confirmed by qRT-PCR.
+|}
+:'''Links:''' [[Granulosa cell]] | [[Oocyte Development]] | [[Sheep Development]]
+===Reference===
+<pubmed>26540452</pubmed>| [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141482 PLoS One.]
+====Copyright====
+© 2015 Bonnet et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+Bonnet A, Servin B, Mulsant P, Mandon-Pepin B (2015) Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Folliculogenesis: Integrated Transcriptomic Study and Molecular Signature of Early Follicular Growth. PLoS ONE 10(11): e0141482. doi:10.1371/journal.pone.0141482
+Fig 9. journal.pone.0141482.g009.jpg
+{{Footer}}
+[[Category:Sheep]]