Endocrine - Adrenal Development: Difference between revisions

Revision as of 13:08, 25 April 2010

Richly vascularized - arterioles passing through cortex, capillaries from cortex to medulla, portal-like circulation
Fetal Cortex - produces a steroid precursor (DEA), converted by placenta into estrogen
Adult Medulla - produces adrenalin (epinephrine), noradrenaline (norepinephrine)
Fetal adrenal hormones - influence lung maturation

Adrenal cortical hormones - (steroids) Cortisol, Aldosterone, Dehydroepiandrosterone

zona glomerulosa - regulated by renin-angiotensin-aldosterone system controlled by the juxtaglomerular apparatus of the kidney.
zona fasciculata - regulated by hypothalamo-pituitary axis with the release of CRH and ACTH respectively.

Adrenal medullary hormones - (amino acid derivatives) Epinephrine, Norepinephrine

Week 10 adrenal gland

Fetal Adrenals - fetal cortex later replaced by adult cortex
Week 6 - fetal cortex, from mesothelium adjacent to dorsal mesentery; Medulla, neural crest cells from adjacent sympathetic ganglia
Adult cortex - mesothelium mesenchyme encloses fetal cortex

Adrenal Cortex

Adrenal Medulla

neural crest origin, migrate adjacent to coelomic cavity, initially uncapsulated and not surrounded by fetal cortex, cells have neuron-like morphology
2 cell types - secrete epinepherine (adrenaline) 80%; secrete norepinepherine (noradrenaline* 20%

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Cite this page: Hill, M.A. (2024, June 1) Embryology Endocrine - Adrenal Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Endocrine_-_Adrenal_Development

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 ===Adult Histology===
 <gallery>
-File:Pineal_histology_001.jpg|Pineal (high power)
 </gallery>