File:Mouse- forelimb-bud-Tbx3-Tbx2.jpg: Difference between revisions

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(Mouse forelimb bud Tbx3 and Tbx2 expression. Establishment of posterior forelimb bud identity requires Hand2. * E9.75 - 27 somites * E9.75 - 27 somites * E10.0 - 30 somites * E10.25 - 32 somites * E10.5: - 35 somites Excerpt from original File name:)
 
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Mouse  forelimb bud Tbx3 and Tbx2 expression.
==Mouse  forelimb bud Tbx3 and Tbx2 expression==


Establishment of posterior forelimb bud identity requires Hand2.
Establishment of posterior forelimb bud identity requires Hand2. Hand2 participates in transcriptional activation and/or upregulation of Tbx2/3 and Shh expression in the posterior mesenchyme and is required for anterior restriction of Gli3 and Alx4 expression.  


* E9.75 -  27 somites
* E9.75 -  27 somites
* E9.75 - 27 somites
* E10.0 - 30 somites
* E10.0 - 30 somites
* E10.25 - 32 somites
* E10.25 - 32 somites
* E10.5: - 35 somites
* E10.5: - 35 somites


===Reference===
<pubmed>20386744</pubmed>| [http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000901 PLoS Genet.]


Excerpt from original File name: Journal.pgen.1000901.g003.png


Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. Galli A, Robay D, Osterwalder M, Bao X, Bénazet JD, Tariq M, Paro R, Mackem S, Zeller R. PLoS Genet. 2010 Apr 8;6(4):e1000901. [http://www.ncbi.nlm.nih.gov/pubmed/20386744 PMID: 20386744]
====Copyright====
This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.


Citation: Galli A, Robay D, Osterwalder M, Bao X, Bénazet J-D, et al. (2010) Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development. PLoS Genet 6(4): e1000901. doi:10.1371/journal.pgen.1000901
Citation: Galli A, Robay D, Osterwalder M, Bao X, Bénazet J-D, et al. (2010) Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development. PLoS Genet 6(4): e1000901. doi:10.1371/journal.pgen.1000901


Editor: Clifford J. Tabin, Harvard Medical School, United States of America
Excerpt from original File name: Journal.pgen.1000901.g003.png


Received: September 11, 2009; Accepted: March 9, 2010; Published: April 8, 2010
This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.


[[Category:Limb]] [[Category:Mouse]] [[Category:Tbx]]
[[Category:Limb]] [[Category:Mouse]] [[Category:Tbx]] [[Category:Mouse E10]]  [[Category:Mouse E10.5]]

Latest revision as of 14:15, 13 February 2014

Mouse forelimb bud Tbx3 and Tbx2 expression

Establishment of posterior forelimb bud identity requires Hand2. Hand2 participates in transcriptional activation and/or upregulation of Tbx2/3 and Shh expression in the posterior mesenchyme and is required for anterior restriction of Gli3 and Alx4 expression.

  • E9.75 - 27 somites
  • E10.0 - 30 somites
  • E10.25 - 32 somites
  • E10.5: - 35 somites

Reference

<pubmed>20386744</pubmed>| PLoS Genet.


Copyright

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

Citation: Galli A, Robay D, Osterwalder M, Bao X, Bénazet J-D, et al. (2010) Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development. PLoS Genet 6(4): e1000901. doi:10.1371/journal.pgen.1000901

Excerpt from original File name: Journal.pgen.1000901.g003.png

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current03:08, 26 April 2010Thumbnail for version as of 03:08, 26 April 2010955 × 436 (45 KB)S8600021 (talk | contribs)Mouse forelimb bud Tbx3 and Tbx2 expression. Establishment of posterior forelimb bud identity requires Hand2. * E9.75 - 27 somites * E9.75 - 27 somites * E10.0 - 30 somites * E10.25 - 32 somites * E10.5: - 35 somites Excerpt from original File name: