File:Zebrafish Wdr18 expression 02.jpg

Zebrafish Wdr18 Expression

wdr18 expression is detected around the Kupffer's vesicle (white arrowhead) at the 6-somite stage. Inset is an overexposed magnified image showing elevated wdr18 expression around the KV. (See also full figure)

• Kupffer's vesicle - (ciliated organ of asymmetry, primitive node) a transient epithelial fluid-filled sac located midventrally posterior to the yolk cell or its extension. The vesicle has been described as equivalent to the primitive node for establishing embryo left-right (L-R) axis.
• Wdr18 - is a member of the WD-repeat protein family found in all eukaryotes. The WD repeat consists of a 44 to 60 amino acid residue sequence that typically contains a GH dipeptide located 11 to 24 residues from its N-terminus and ends with a WD dipeptide at its C-terminus. Wdr18 is maternally expressed from the 1–4 cell stage.

Links: Image - full figure | Image - Panel C | Zebrafish Development

Reference

<pubmed>21876750</pubmed>| PLoS One.

Copyright

© 2011 Gao et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. journal.pone.0023386.g001.jpg doi:10.1371/journal.pone.0023386.g001 original figure cropped panel C, altered in size and labeling.