File:Sheep follicle gene expression 01.jpg

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Sheep Follicle Gene Expression

  • red - genes expressed in granulose cells.
  • blue - genes expressed in oocytes.
  • black - genes expressed both in oocytes and granulosa cells.

Follicle type and diameter

  • primordial (PD) < 35 μM
  • primary (PM) 35 – 50 μM
  • secondary follicles (SC) 60 – 120 μM
  • small antral follicles (SA) 250 – 500 μM
 Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG).

They were selected using pairwise comparisons (nbinom Test) comparing each stage to the others including multi-tissue samples (FDR<5% and a fold change >3 for granulosa samples and a fold change >-10 for oocyte samples). Their differential expression was confirmed by qRT-PCR.

Links: Granulosa cell | Oocyte Development | Sheep Development

Reference

<pubmed>26540452</pubmed>| PLoS One.

Copyright

© 2015 Bonnet et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Bonnet A, Servin B, Mulsant P, Mandon-Pepin B (2015) Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Folliculogenesis: Integrated Transcriptomic Study and Molecular Signature of Early Follicular Growth. PLoS ONE 10(11): e0141482. doi:10.1371/journal.pone.0141482

Fig 9. journal.pone.0141482.g009.jpg


Cite this page: Hill, M.A. (2024, April 27) Embryology Sheep follicle gene expression 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Sheep_follicle_gene_expression_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current22:11, 12 November 2015Thumbnail for version as of 22:11, 12 November 20151,235 × 1,000 (168 KB)Z8600021 (talk | contribs)Fig 9. Distribution of the expression of the 24 biomarkers during early follicular development. These biomarkers correspond to the most strongly expressed genes in a specific cell type and stage (PDO, PMO, SCO, SAO, PDG, PMG, SCG, SAG). They were selec...

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