File:Neural - Human hippocampus marker expression.jpg
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Human hippocampus marker expression
Summary of marker expression in the human hippocampus related to the milestones of adult hippocampal neurogenesis in rodents.
The frame indicates the stages of adult neurogenesis covered in this study: all additional markers were tested together with DCX.
Marker combinations that we could detect in our samples are marked with a green check.
Not all markers were found at all ages, see paper Figs. 6 for details.
Reference
Knoth R, Singec I, Ditter M, Pantazis G, Capetian P, Meyer RP, Horvat V, Volk B & Kempermann G. (2010). Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years. PLoS ONE , 5, e8809. PMID: 20126454 DOI.
Copyright
© 2010 Knoth et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Original File Name: Figure 10. Journal.pone.0008809.g010.jpg http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0008809&imageURI=info:doi/10.1371/journal.pone.0008809.g010
- "Our data suggest that in the adult human hippocampus neurogenesis-associated features that have been identified in rodents show patterns, as well as qualitative and quantitative age-related changes, that are similar to the course of adult hippocampal neurogenesis in rodents. Consequently, although further validation as well as the application of independent methodology (e.g. electron microscopy and cell culture work) is desirable, our data will help to devise the framework for specific research on cellular plasticity in the aging human hippocampus."
Cite this page: Hill, M.A. (2024, April 26) Embryology Neural - Human hippocampus marker expression.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Neural_-_Human_hippocampus_marker_expression.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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