User:Z3292953: Difference between revisions
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===Lab 1=== | ===Lab 1=== | ||
'''Question 1''' | |||
-The first in vitro birth was Louise Brown in 1978 in The UK. The Nobel prize went to Robert G Edwards in 2010 | -The first in vitro birth was Louise Brown in 1978 in The UK. The Nobel prize went to Robert G Edwards in 2010 | ||
'''Question 2''' | |||
- Pregnancy after Age 50: Defining Risks for Mother and Child. | - Pregnancy after Age 50: Defining Risks for Mother and Child. | ||
Kort DH, Gosselin J, Choi JM, Thornton MH, Cleary-Goldman J, Sauer MV. | Kort DH, Gosselin J, Choi JM, Thornton MH, Cleary-Goldman J, Sauer MV. | ||
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The paper discusses the risks involved with pregancy for women over 50 years of age. It compares risks such as gestational diabetes, hypertensive disorders and abnormal placentation for women over 50 with women under 50. | The paper discusses the risks involved with pregancy for women over 50 years of age. It compares risks such as gestational diabetes, hypertensive disorders and abnormal placentation for women over 50 with women under 50. | ||
'''Question 3''' | |||
- Spina bifida and atrial septal defect | - Spina bifida and atrial septal defect | ||
--[[User:Z3292953|z3292953]] 21:36, 3 August 2011 (EST) | --[[User:Z3292953|z3292953]] 21:36, 3 August 2011 (EST) | ||
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===Lab 2=== | ===Lab 2=== | ||
'''Question 1''' | |||
Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation. | Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation. | ||
The protein that binds sperm is zonapellucida 3. After fertilisation, enzymes affect ZP3 modifying it, which causes it to not be able to bind. | The protein that binds sperm is zonapellucida 3. After fertilisation, enzymes affect ZP3 modifying it, which causes it to not be able to bind. | ||
'''Question 2''' | |||
Identify a review and a research article related to your group topic. | Identify a review and a research article related to your group topic. | ||
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===Lab 3=== | ===Lab 3=== | ||
'''Image uploaded in Lab 2''' | |||
[[File:Differentially expressed RefSeq genes in human trisomy 21.jpg|thumb|Differentially expressed RefSeq genes in human trisomy 21]] | [[File:Differentially expressed RefSeq genes in human trisomy 21.jpg|thumb|Differentially expressed RefSeq genes in human trisomy 21]] | ||
'''Question 1''' | |||
What is the maternal dietary requirement for late neural development? | What is the maternal dietary requirement for late neural development? | ||
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'''Question 2''' | |||
Upload a picture relating to you group project. | Upload a picture relating to you group project. | ||
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===Lab 4=== | ===Lab 4=== | ||
'''Question 1''' | |||
The allantois, identified in the placental cord, is continuous with what anatomical structure? | The allantois, identified in the placental cord, is continuous with what anatomical structure? | ||
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The allantois extends into the connecting stalk and gives rise to the umbilical cord. It eventually becomes the urachus in the bladder of an adult. The urachus is also referred to as the median umbilical ligament. | The allantois extends into the connecting stalk and gives rise to the umbilical cord. It eventually becomes the urachus in the bladder of an adult. The urachus is also referred to as the median umbilical ligament. | ||
'''Question 2''' | |||
Identify the 3 vascular shunts, and their location, in the embryonic circulation. | Identify the 3 vascular shunts, and their location, in the embryonic circulation. | ||
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3. Foramen Ovale - connects the two atria | 3. Foramen Ovale - connects the two atria | ||
'''Question 3''' | |||
Identify the Group project sub-section that you will be researching. | Identify the Group project sub-section that you will be researching. | ||
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===Lab 5=== | ===Lab 5=== | ||
'''Question 1''' | |||
Which side (L/R) is most common for diaphragmatic hernia and why? | Which side (L/R) is most common for diaphragmatic hernia and why? | ||
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===Lab 6=== | ===Lab 6=== | ||
'''Question 1''' | |||
What week of development do the palatal shelves fuse? | What week of development do the palatal shelves fuse? | ||
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The palatal shelves fuse in week 9 of development. | The palatal shelves fuse in week 9 of development. | ||
'''Question 2''' | |||
What early animal model helped elucidate the neural crest origin and migration of neural crest cells? | What early animal model helped elucidate the neural crest origin and migration of neural crest cells? | ||
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The chicken model. | The chicken model. | ||
'''Question 3''' | |||
What abnormality results from neural crest not migrating into the cardiac outflow tract? | What abnormality results from neural crest not migrating into the cardiac outflow tract? | ||
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===Lab 7=== | ===Lab 7=== | ||
'''Question 1''' | |||
Are satellite cells (a) necessary for muscle hypertrophy and (b) generally involved in hypertrophy? | Are satellite cells (a) necessary for muscle hypertrophy and (b) generally involved in hypertrophy? | ||
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(b) They are, however, generally involved as they proliferate and differentiate during muscle hypertrophy. | (b) They are, however, generally involved as they proliferate and differentiate during muscle hypertrophy. | ||
'''Question 2''' | |||
Why does chronic low frequency stimulation cause a fast to slow fibre type shift? | Why does chronic low frequency stimulation cause a fast to slow fibre type shift? | ||
Revision as of 20:22, 28 September 2011
Lab 4 Online Assessment
- The allantois, identified in the placental cord, is continuous with what anatomical structure?
- Identify the 3 vascular shunts, and their location, in the embryonic circulation.
- Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)
--[[User:Z3292953 13:17, 3 August 2011 (EST)
Lab Attendance
Lab 2- I was here for Lab 2, you saw me but I didn't do lab attendance.
Lab 3- --z3292953 11:03, 11 August 2011 (EST)
Lab 4- --z3292953 11:09, 18 August 2011 (EST)
Lab 5- --z3292953 11:26, 25 August 2011 (EST)
Lab 6- --z3292953 11:26, 1 September 2011 (EST)
Lab 7- --z3292953 11:02, 15 September 2011 (EST)
Lab 8- --z3292953 11:17, 22 September 2011 (EST)
Individual Assessment
Lab 1
Question 1 -The first in vitro birth was Louise Brown in 1978 in The UK. The Nobel prize went to Robert G Edwards in 2010
Question 2 - Pregnancy after Age 50: Defining Risks for Mother and Child. Kort DH, Gosselin J, Choi JM, Thornton MH, Cleary-Goldman J, Sauer MV. Am J Perinatol. 2011 Aug 1. [Epub ahead of print] PMID: 21809262 [PubMed - as supplied by publisher]
The paper discusses the risks involved with pregancy for women over 50 years of age. It compares risks such as gestational diabetes, hypertensive disorders and abnormal placentation for women over 50 with women under 50.
Question 3 - Spina bifida and atrial septal defect --z3292953 21:36, 3 August 2011 (EST)
Lab 2
Question 1
Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation. The protein that binds sperm is zonapellucida 3. After fertilisation, enzymes affect ZP3 modifying it, which causes it to not be able to bind.
Question 2
Identify a review and a research article related to your group topic. Novel concepts in evaluating antimicrobial therapy for bacterial lung infections in patients with cystic fibrosis.Rogers GB, Hoffman LR, Döring G. J Cyst Fibros.2011 Jul 18. [Epub ahead of print]
Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis.McNally P, Coughlan C, Bergsson G, Doyle M, Taggart C, Adorini L, Uskokovic MR, El-Nazir B, Murphy P, Greally P, Greene CM, McElvaney NG.J Cyst Fibros. 2011 Jul 22. [Epub ahead of print]
--z3292953 15:43, 9 August 2011 (EST)
Lab 3
Image uploaded in Lab 2
Question 1
What is the maternal dietary requirement for late neural development?
Both maternal dietary folate and choline are important in late neural development. A deficiency in these may result in abnormalities. PMC2869500
Question 2
Upload a picture relating to you group project.
--Mark Hill 12:13, 16 August 2011 (EST) Better, but you really do not need to call the image "File".
What was wrong with "Mouse - Perinatal lethality and cleft palate deletion from Ube3a to Gabrb3" or "Lethality and cleft palate mice homozygous deleted Ube3a to Gabrb3".
--z3292953 12:03, 16 August 2011 (EST)
Lab 4
Question 1
The allantois, identified in the placental cord, is continuous with what anatomical structure?
The allantois extends into the connecting stalk and gives rise to the umbilical cord. It eventually becomes the urachus in the bladder of an adult. The urachus is also referred to as the median umbilical ligament.
Question 2
Identify the 3 vascular shunts, and their location, in the embryonic circulation.
1. Ductus Arteriosus - connects the pulmonary artery and the descending aorta
2. Ductus Venosus - connects the inferior vena cava and the umbilica
3. Foramen Ovale - connects the two atria
Question 3
Identify the Group project sub-section that you will be researching.
For the group project I will be researching Developmental Staging and Abnormality Classification.
--z3292953 11:19, 24 August 2011 (EST)
Lab 5
Question 1
Which side (L/R) is most common for diaphragmatic hernia and why?
The most common side for diaphragmatic hernia is the left side. This is due to the pleuroperitinal canal being larger on the left side than on the right. It may also be due the fact that the left side closes slightly later than the right.
--z3292953 10:08, 1 September 2011 (EST)
Lab 6
Question 1
What week of development do the palatal shelves fuse?
The palatal shelves fuse in week 9 of development.
Question 2
What early animal model helped elucidate the neural crest origin and migration of neural crest cells?
The chicken model.
Question 3
What abnormality results from neural crest not migrating into the cardiac outflow tract?
Tetralogy of Fallot
--z3292953 16:34, 14 September 2011 (EST)
Lab 7
Question 1
Are satellite cells (a) necessary for muscle hypertrophy and (b) generally involved in hypertrophy?
(a) Studies have shown that satellite cells are not necessary for muscle hypertrophy (b) They are, however, generally involved as they proliferate and differentiate during muscle hypertrophy.
Question 2
Why does chronic low frequency stimulation cause a fast to slow fibre type shift?
It mimics the impulse patterns of a slow. This impulse pattern induces the transformation of fast to slow.
Trisomy 21 Discussion
- The introduction is good
- There are a lot of subheadings, maybe some of them could be combined
- Recent findings might be better towards the end of the page
- The links at the end of the subheadings are good
- The "Screening by Country" section should contain more than one country
- The Prevalence section could also use more examples
- Some of the images need to be properly referenced
- It may have been good to include some backgorund information
- Some of the images, especially the John Down one, didnt seem to fit in the section where they were placed and would be bettter used somewhere more relevent.
--z3292953 12:13, 21 September 2011 (EST)
Peer Assessments
Group 1
- Overall the page was good. There were only a few mistakes identified.
- The Intro was good, it described the disease and gave the reader an idea of what to expect of the page. However, it could do with an image.
- The graph in the epidemiology section is missing the copyright information.
- There doesnt seem to be enough referencing in the etiology section. However, this section was good and the links to the glossary are helpful.
- Clinical manifestions was well set out and easy to read. The use of referencing was good, it shows that a lot of research was done.
- Postnatal Diagnosis appears to be missing an image in the table.
- A few of the words in the glossary section are missing their definitions.
Group 2
Group 3
Group 4
Group 5
Group 6
Group 7
Group 8
Group 9
Group 10
Reference
- ↑ <pubmed>2924885</pubmed>
