User:Z3291643
Lab 4 Online Assessment
- The allantois, identified in the placental cord, is continuous with what anatomical structure?
- Identify the 3 vascular shunts, and their location, in the embryonic circulation.
- Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)
--Z3291643 12:55, 28 July 2011 (EST)
Lab 1 Assessment
1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique.
‘in vitro’ fertilization is Latin for ‘in glass’ fertilization and is a treatment for infertility, whereby the sperm fertilizes the ovum outside the body and is then implanted back into the patient’s uterus. The first successful IVF birth, Louise Brown, occurred in 1978 with the help of Patrick Steptoe and Robert Edwards. Edwards was awarded the 2010 nobel prize in medicine for his achievement.
2. Identify a recent paper on fertilisation and describe its key findings.
The aim of this paper was to investigate whether age <=25 played a role in the reproductive outcome of women undergoing IVF. Infertile patients aged between 19 and 25 years of age were compared to infertile patients aged 30-35 years to determine primarily fertilization rates and the number of top quality embryos. The results were unexpected as the younger subjects had lower fertilization rates and reduced embryo quality. [1]
3. Identify 2 congenital anomalies.
Trisomy 21 and cleft palate
References
Nazemian Z, Esfandiari N, Javed M, Casper RF. (2011) The effect of age on in vitro fertilization outcome: is too young possible? J Assist Reprod Genet. 25: 101-106.
--Mark Hill 10:01, 3 August 2011 (EST) These answers are fine.
--Sang Lee 13:02, 4 August 2011 (EST)
Lab 2 Assessment
1. Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilization.
ZP3 acts as a receptor for the sperm. This is followed by the acrosome reaction, whereby acrosomal contents digest the ZP and allow the sperm surface proteins to bind to the ZP2. After fertilization, cortical reaction takes place where cortical granules are exocytosed. This results in the removal of carbohydrate from ZP3, changing it to prevent polyspermy.
2. Identify a review and a research article related to your group topic.
- ↑ <pubmed>21042842</pubmed>
