User:Z3289301
Lab 4 Online Assessment
- The allantois, identified in the placental cord, is continuous with what anatomical structure?
- Identify the 3 vascular shunts, and their location, in the embryonic circulation.
- Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)
--Z3289301 12:55, 28 July 2011 (EST)
--Mark Hill 09:38, 3 August 2011 (EST) All 3 questions from Lab 1 need to be completed before Lab 2
Lab 1 - Online Assessment
1.Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique.
The introduction of In Vitro Fertilization (IVF) dates back to the late 1800's where a team from the University of Cambridge, England, attempted and succeeded in transplanting embryos in rabbits. After many years, in 1959, Chang MC experienced a breakthrough as he succeeded in fertilizing a rabbit ova in vitro. Finally, through Patrick Steptoe and Robert Edwards' research, the first IVF human baby,Louise Brown, was born in England, 1978.
The Robert Edwards received the 2010 Nobel Prize associated with IVF.
2. Identify a recent paper on fertilisation and describe its key findings
The key findings: 1. The success rate of IVF when using fresh testicular sperm is similar to using cryopreserved testicular sperm. 2. Even if fresh testicular sperm lacks motility, it can still be cryopreserved and used for later an IVF treatment as the outcome is still favourable.
Reference: Levron, J.; Madgar, I.; Shefi, S.; Meirow, D.; Wiser, A.; Bider, D.; Dor, J.; Raviv, G.(2011) IVF outcome with cryopreserved testicular sperm. Andrologia,43:1.DOI: 10.1111/j.1439-0272.2009.01014.
3. Identify 2 congenital anomalies.
1. Hypospadias 2. Trisomy 21 (Down’s syndrome)
--Dona Cho 18:34, 3 August 2011 (EST)
--Dona Cho 13:01, 4 August 2011 (EST)
Lab 2 - Online Assessment
1. Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation.
ZP3 is the sperm receptor. After fertilisation, a carbohydrates on the ZP3 is modified or removed. This then means that ZP3 can no longer bind to another sperm, preventing polysermy.
2. Identify a review and a research article related to your group topic.
Review article: [1]
Research article: [2]
--Dona Cho 18:05, 10 August 2011 (EST)
