Difference between revisions of "Template:Male Infertility Genes table 1"

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{|
 
{|
|+ Selected genes in Male Infertility
+
|+ '''Selected genes in Male Infertility'''
|-
+
|-bgcolor="CEDFF2"
 
! Gene abbreviation
 
! Gene abbreviation
 
! Name
 
! Name
! Online Mendelian Inheritance in Man ([https://www.omim.org OMIM])
+
! Gene Location
! HUGO Gene Nomenclature Commitee ([https://www.genenames.org HGNC])
+
! Online Mendelian<br>Inheritance in Man ([https://www.omim.org OMIM])
 +
! HUGO Gene Nomenclature<br>Committee ([https://www.genenames.org HGNC])
 
! GeneCards ([https://www.genecards.org GCID])
 
! GeneCards ([https://www.genecards.org GCID])
 
! Diagnosis
 
! Diagnosis
 
|-
 
|-
| AURKC || Aurora kinase C || [https://www.omim.org/entry/603495 603495] || 11391 || GC19P057230 || Macrozoospermia
+
| AURKC || Aurora kinase C || {{Chr19}}q13.43  || [https://www.omim.org/entry/603495 603495] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11391 11391] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC19P057230 GC19P057230] || Macrozoospermia
|-
+
|-bgcolor="F5FAFF"
| CATSPER1 || Cation channel sperm-associated 1 || [https://www.omim.org/entry/606389 606389] || 17116 || GC11M066034 || Asthenozoospermia
+
| CATSPER1 || Cation channel sperm-associated 1 || {{Chr11}}q13.1   || [https://www.omim.org/entry/606389 606389] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:17116 17116] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC11M066034 GC11M066034] || Asthenozoospermia
|-
 
| CFTR || Cystic fibrosis transmembrane conductance regulator || [https://www.omim.org/entry/602421 602421] || 1884 || GC07P117465 || Obstructive azoospermia
 
|-
 
| DNAH1 || Dynein axonemal heavy chain 1 || [https://www.omim.org/entry/603332 603332] || 2940 || GC03P052350 || Asthenozoospermia
 
|-
 
| DPY19L2 || Dpy-19-like 2 gene || [https://www.omim.org/entry/613893 613893] || 19414 || GC12M063558 || Globozoospermia
 
|-
 
| GALNTL5 || Polypeptide N-acetylgalactosaminyltransferase-like 5 || [https://www.omim.org/entry/615133 615133] || 21725 || GC07P151956 || Asthenozoospermia
 
|-
 
| MAGEB4 || MAGE family member B4 || [https://www.omim.org/entry/300153 300153] || 6811 || GC0XP030260 || Azoospermia
 
|-
 
| NANOS1 || Nanos C2HC-type zinc finger 1 || [https://www.omim.org/entry/608226 608226] || 23044 || GC10P119029 || Azoospermia
 
|-
 
| NR0B1 || Nuclear receptor subfamily 0 group B member 1 || [https://www.omim.org/entry/300473 300473] || 7960 || GC0XM030322 || Azoospermia
 
|-
 
| NR5A1 || Nuclear receptor subfamily 5 group A member 1 || [https://www.omim.org/entry/184757 184757] || 7983 || GC09M124481 || Azoospermia
 
|-
 
| SOHLH1 || Spermatogenesis and oogenesis-specific basic helix–loop–helix 1 || [https://www.omim.org/entry/610224 610224] || 27845 || GC09M135693 || Azoospermia
 
 
|-
 
|-
| vSPATA16 || Spermatogenesis-associated 16 || [https://www.omim.org/entry/609856 609856] || 29935 || GC03M172889 || Globozoospermia
+
| CFTR || Cystic fibrosis transmembrane conductance regulator || {{Chr7}}q31.2  || [https://www.omim.org/entry/602421 602421] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:1884 1884] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC07P117465 GC07P117465] || Obstructive azoospermia
 +
|-bgcolor="F5FAFF"
 +
| DNAH1 || Dynein axonemal heavy chain 1 || {{Chr3}}p21.1  || [https://www.omim.org/entry/603332 603332] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:2940 2940] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC03P052350 GC03P052350] || Asthenozoospermia
 
|-
 
|-
| SYCE1 || Synaptonemal complex central element protein 1 || [https://www.omim.org/entry/611486 611486] || 28852 || GC10M133553 || Azoospermia
+
| DPY19L2 || Dpy-19-like 2 gene || {{Chr12}}q14.2  || [https://www.omim.org/entry/613893 613893] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:19414 19414] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC12M063558 GC12M063558] || Globozoospermia
 +
|-bgcolor="F5FAFF"
 +
| GALNTL5 || Polypeptide N-acetylgalactosaminyltransferase-like 5 || {{Chr7}}q36.1 || [https://www.omim.org/entry/615133 615133] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:21725 21725] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC07P151956 GC07P151956] || Asthenozoospermia
 
|-
 
|-
| TAF4B || TATA-box binding protein-associated factor 4b || [https://www.omim.org/entry/601689 601689] || 11538 || GC18P026225 || Azoospermia
+
| MAGEB4 || MAGE family member B4 || {{ChrX}}p21.2  || [https://www.omim.org/entry/300153 300153] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:6811 6811] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC0XP030260 GC0XP030260] || Azoospermia
 +
|-bgcolor="F5FAFF"
 +
| NANOS1 || Nanos C2HC-type zinc finger 1 || {{Chr10}}q26.11  || [https://www.omim.org/entry/608226 608226] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:23044 23044] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC10P119029 GC10P119029] || Azoospermia
 
|-
 
|-
| TEX11 || Testis expressed 11 || [https://www.omim.org/entry/300311 300311] || 11733 || GC0XM070528 || Azoospermia
+
| NR0B1 || Nuclear receptor subfamily 0 group B member 1 || {{ChrX}}p21.2  || [https://www.omim.org/entry/300473 300473] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:7960 7960] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC0XM030322 GC0XM030322] || Azoospermia
 +
|-bgcolor="F5FAFF"
 +
| NR5A1 || Nuclear receptor subfamily 5 group A member 1 || {{Chr9}}q33.3  || [https://www.omim.org/entry/184757 184757] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:7983 7983] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC09M124481 GC09M124481] || Azoospermia
 
|-
 
|-
| TEX15 || Testis expressed 15, meiosis and synapsis associated || [https://www.omim.org/entry/605795 605795] || 11738 || GC08M030808 || Azoospermia
+
| SOHLH1 || Spermatogenesis and oogenesis-specific basic helix–loop–helix 1 || {{Chr9}}q34.3 || [https://www.omim.org/entry/610224 610224] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:27845 27845] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC09M135693 C09M135693] || Azoospermia
 +
|-bgcolor="F5FAFF"
 +
| vSPATA16 || Spermatogenesis-associated 16 || {{Chr3}}q26.31 || [https://www.omim.org/entry/609856 609856] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:29935 29935] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC03M172889 GC03M172889] || Globozoospermia
 
|-
 
|-
| WT1 || Wilms tumour 1 || [https://www.omim.org/entry/607102 607102] || 12796 || GC11M032365 || Azoospermia
+
| SYCE1 || Synaptonemal complex central element protein 1 || {{Chr10}}q26.3  || [https://www.omim.org/entry/611486 611486] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:28852 28852] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC10M133553 GC10M133553] || Azoospermia
 +
|-bgcolor="F5FAFF"
 +
| TAF4B || TATA-box binding protein-associated factor 4b ||  {{Chr18}}q11.2 || [https://www.omim.org/entry/601689 601689] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11538 11538] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC18P026225 GC18P026225] || Azoospermia
 
|-
 
|-
| ZMYND15 || Zinc-finger MYND-type containing 15 || [https://www.omim.org/entry/614312 614312] || 20997 || GC17P004740 || Azoospermia
+
| TEX11 || Testis expressed 11 || {{ChrX}}q13.1  || [https://www.omim.org/entry/300311 300311] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11733 11733] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC0XM070528 GC0XM070528] || Azoospermia
 +
|-bgcolor="F5FAFF"
 +
| TEX15 || Testis expressed 15, meiosis and synapsis associated || {{Chr8}}p12  || [https://www.omim.org/entry/605795 605795] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:11738 11738] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC08M030808 GC08M030808] || Azoospermia
 
|-
 
|-
| Colspan=5|Data source{{#pmid:29199274|PMID29199274}} (table 1) &nbsp;&nbsp;'''Links:'''
+
| WT1 || Wilms tumour 1 ||  {{Chr8}}p12  || [https://www.omim.org/entry/607102 607102] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:12796 12796] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC11M032365 GC11M032365] || Azoospermia
|}
+
|-bgcolor="F5FAFF"
 +
| ZMYND15 || Zinc-finger MYND-type containing 15 || {{Chr17}}p13.2  || [https://www.omim.org/entry/614312 614312] || [https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:20997 20997] || [https://www.genecards.org/cgi-bin/carddisp.pl?gene=GC17P004740 GC17P004740] || Azoospermia
 +
|-bgcolor="F5FFFA"
 +
| Colspan=7| &nbsp;&nbsp;Table data source{{#pmid:29199274|PMID29199274}} (table 1)&nbsp;&nbsp;&nbsp;&nbsp;'''Links:''' {{Fertilization}} | {{spermatozoa}} | {{testis}} | [[Template:Male Infertility Genes table 1|Male Infertility Genes]] | [[Template:Female Infertility Genes table 1|Female Infertility Genes]] | {{oocyte}} | {{ovary}} | [[Abnormal Development - Genetic|Genetic Abnormalities]] | {{ART}}<br>
 +
&nbsp;&nbsp;Asthenozoospermia - (asthenospermia) term for reduced {{spermatozoa}} motility. Azoospermia - term for no {{spermatozoa}} located in the ejaculate. Globozoospermia - term for {{spermatozoa}} with a round head and no {{acrosome}}.
 +
|}<noinclude>[[Category:Table]][[Category:Fertilization]][[Category:Spermatozoa]][[Category:Testis]][[Category:Male]][[Category:Abnormal Development]]</noinclude>

Latest revision as of 18:02, 23 October 2018

Selected genes in Male Infertility
Gene abbreviation Name Gene Location Online Mendelian
Inheritance in Man (OMIM)
HUGO Gene Nomenclature
Committee (HGNC)
GeneCards (GCID) Diagnosis
AURKC Aurora kinase C 19q13.43 603495 11391 GC19P057230 Macrozoospermia
CATSPER1 Cation channel sperm-associated 1 11q13.1 606389 17116 GC11M066034 Asthenozoospermia
CFTR Cystic fibrosis transmembrane conductance regulator 7q31.2 602421 1884 GC07P117465 Obstructive azoospermia
DNAH1 Dynein axonemal heavy chain 1 3p21.1 603332 2940 GC03P052350 Asthenozoospermia
DPY19L2 Dpy-19-like 2 gene 12q14.2 613893 19414 GC12M063558 Globozoospermia
GALNTL5 Polypeptide N-acetylgalactosaminyltransferase-like 5 7q36.1 615133 21725 GC07P151956 Asthenozoospermia
MAGEB4 MAGE family member B4 Xp21.2 300153 6811 GC0XP030260 Azoospermia
NANOS1 Nanos C2HC-type zinc finger 1 10q26.11 608226 23044 GC10P119029 Azoospermia
NR0B1 Nuclear receptor subfamily 0 group B member 1 Xp21.2 300473 7960 GC0XM030322 Azoospermia
NR5A1 Nuclear receptor subfamily 5 group A member 1 9q33.3 184757 7983 GC09M124481 Azoospermia
SOHLH1 Spermatogenesis and oogenesis-specific basic helix–loop–helix 1 9q34.3 610224 27845 C09M135693 Azoospermia
vSPATA16 Spermatogenesis-associated 16 3q26.31 609856 29935 GC03M172889 Globozoospermia
SYCE1 Synaptonemal complex central element protein 1 10q26.3 611486 28852 GC10M133553 Azoospermia
TAF4B TATA-box binding protein-associated factor 4b 18q11.2 601689 11538 GC18P026225 Azoospermia
TEX11 Testis expressed 11 Xq13.1 300311 11733 GC0XM070528 Azoospermia
TEX15 Testis expressed 15, meiosis and synapsis associated 8p12 605795 11738 GC08M030808 Azoospermia
WT1 Wilms tumour 1 8p12 607102 12796 GC11M032365 Azoospermia
ZMYND15 Zinc-finger MYND-type containing 15 17p13.2 614312 20997 GC17P004740 Azoospermia
  Table data source[1] (table 1)    Links: fertilization | spermatozoa | testis | Male Infertility Genes | Female Infertility Genes | oocyte | ovary | Genetic Abnormalities | ART

  Asthenozoospermia - (asthenospermia) term for reduced spermatozoa motility. Azoospermia - term for no spermatozoa located in the ejaculate. Globozoospermia - term for spermatozoa with a round head and no acrosome.

  1. Harper JC, Aittomäki K, Borry P, Cornel MC, de Wert G, Dondorp W, Geraedts J, Gianaroli L, Ketterson K, Liebaers I, Lundin K, Mertes H, Morris M, Pennings G, Sermon K, Spits C, Soini S, van Montfoort APA, Veiga A, Vermeesch JR, Viville S & Macek M. (2018). Recent developments in genetics and medically assisted reproduction: from research to clinical applications. Eur. J. Hum. Genet. , 26, 12-33. PMID: 29199274 DOI.