Template:Main Page News: Difference between revisions

From Embryology
mNo edit summary
mNo edit summary
 
(26 intermediate revisions by the same user not shown)
Line 1: Line 1:
{| width=800px|
{| width=800px|
|-bgcolor="CEDFF2"  
|-bgcolor="CEDFF2"  
| <span style="font-size:150%">'''News - Rare Sesquizygotic Twinning'''</span>
| <span style="font-size:150%">'''News - Complete human day 14 post-implantation embryo models from naïve Embryonic Stem Cells'''</span>
|-bgcolor="F5FAFF"  
|-bgcolor="F5FAFF"  
| valign=top|[[File:Smellie1754_table_10_twins.jpg|thumb|150px|alt=Twinning historic drawing|link=Abnormal Development - Twinning|Twinning historic drawing by William Smellie (1697-1763)]]
| valign=top|[[File:Stage6 bf03.jpg|thumb|150px|alt=Carnegie Stage 6 Embryo|Carnegie Stage 6 Embryo]]
<br>Sesquizygotic twinning is a rare intermediate form of twinning, lying between mono-zygotic and dizygotic twinning, the twins can be maternally identical but chimerical for their paternal genome. This rare twinning event has been recently identified by a twin {{amniocentesis}} genotyping study<ref name=Ref-Gabbett2019>{{Ref-Gabbett2019}}</ref> that showed twins that were maternally identical, but chimerically shared 78% of their paternal genome.
 
<br>
This recent Nature paper{{#pmid:37673118|PMID37673118}} describes the use of naïve human Embryonic Stem Cells to recapitulate the early stages of human development.
 
"The ability to study human post-implantation development remains limited due to ethical and technical challenges associated with intrauterine development after implantation....only genetically unmodified human naïve human ES cells...recapitulate the organization of nearly all known lineages and compartments of post-implantation human embryos including epiblast, hypoblast, extra-embryonic mesoderm, and trophoblast surrounding the latter layers...These human complete SEMs demonstrated developmental growth dynamics that resemble key hallmarks of post-implantation stage embryogenesis up to 13-14 days post-fertilization (dpf) (Carnegie stage 6a)."
 
:'''Links:''' {{stem cells}} | Carnegie stage {{CS6}}
 
<references/>
<references/>
<br>
'''Links:''' {{twinning}} | {{amniocentesis}} | [https://www.nejm.org/doi/full/10.1056/NEJMoa1701313 NEMJ] | [https://newsroom.unsw.edu.au/news/health/semi-identical-twins-identified-pregnancy-first-time?utm_source=medicine&utm_medium=social-team UNSW News 29Feb2019] | [http://www.ncbi.nlm.nih.gov/pubmed/?term=Sesquizygotic+Twinning Search Pubmed]
{| class="wikitable mw-collapsible mw-collapsed"
{| class="wikitable mw-collapsible mw-collapsed"
! Older News Articles &nbsp;
! Older News Articles &nbsp;
|-
|-
| [[Template_talk:Main_Page_News|'''Older News Articles''']] - [[Template_talk:Main_Page_News#October|Spinal Muscular Atrophy Screening]] | [[Template_talk:Main_Page_News#February|Australian 2018 Pregnancy Care Guidelines]] | [[Template_talk:Main_Page_News#July|CRISPR]] | [[Template_talk:Main_Page_News#June|Ronan O’Rahilly]] | [[Template_talk:Main_Page_News#February|Gestational Diabetes]] | [[Template_talk:Main_Page_News#September|Kyoto eBook]] | [[Template_talk:Main_Page_News#August|Dolly's sisters live on!]] | [[Template_talk:Main_Page_News#June|Thalidomide in Zebrafish]] | [[Template_talk:Main_Page_News#March|Human pancreas stem cells]] | [[Template_talk:Main_Page_News#January|Oral contraceptive no risk of major birth defects]] | [[Template_talk:Main_Page_News#September|Maternal Malaria Neurovascular Development Effects]] | [[Template_talk:Main_Page_News#June|Oocyte/Spermatozoa fate decision]] [[Template_talk:Main_Page_News#April|Rubella eliminated in the Americas]] | [[Template_talk:Main_Page_News#February|Three-person embryos]]
| [[Template_talk:Main_Page_News|'''Older News Articles''']] - [[Template_talk:Main_Page_News#January|Climate Change Abnormal Development]] | [[Template_talk:Main_Page_News#December|Air Pollution]] | [[Template_talk:Main_Page_News#February|Rare Sesquizygotic Twinning]] | [[Template_talk:Main_Page_News#June|Australia's mothers and babies 2017]] | [[Template_talk:Main_Page_News#October|Spinal Muscular Atrophy Screening]] | [[Template_talk:Main_Page_News#February|Australian 2018 Pregnancy Care Guidelines]] | [[Template_talk:Main_Page_News#July|CRISPR]] | [[Template_talk:Main_Page_News#June|Ronan O’Rahilly]]
|}
|}
<center><html5media width="480" height="360">https://www.youtube.com/embed/YH9yA3w6bSI</html5media></center>
<center>[https://youtu.be/YH9yA3w6bSI YouTube video]</center>
|}
|}

Latest revision as of 16:10, 8 September 2023

News - Complete human day 14 post-implantation embryo models from naïve Embryonic Stem Cells
Carnegie Stage 6 Embryo
Carnegie Stage 6 Embryo

This recent Nature paper[1] describes the use of naïve human Embryonic Stem Cells to recapitulate the early stages of human development.

"The ability to study human post-implantation development remains limited due to ethical and technical challenges associated with intrauterine development after implantation....only genetically unmodified human naïve human ES cells...recapitulate the organization of nearly all known lineages and compartments of post-implantation human embryos including epiblast, hypoblast, extra-embryonic mesoderm, and trophoblast surrounding the latter layers...These human complete SEMs demonstrated developmental growth dynamics that resemble key hallmarks of post-implantation stage embryogenesis up to 13-14 days post-fertilization (dpf) (Carnegie stage 6a)."

Links: stem cells | Carnegie stage 6
  1. ↑ Oldak B, Wildschutz E, Bondarenko V, Comar MY, Zhao C, Aguilera-Castrejon A, Tarazi S, Viukov S, Pham TXA, Ashouokhi S, Lokshtanov D, Roncato F, Ariel E, Rose M, Livnat N, Shani T, Joubran C, Cohen R, Addadi Y, Chemla M, Kedmi M, Keren-Shaul H, Pasque V, Petropoulos S, Lanner F, Novershtern N & Hanna JH. (2023). Complete human day 14 post-implantation embryo models from naïve ES cells. Nature , , . PMID: 37673118 DOI.
Older News Articles  
Older News Articles - Climate Change Abnormal Development | Air Pollution | Rare Sesquizygotic Twinning | Australia's mothers and babies 2017 | Spinal Muscular Atrophy Screening | Australian 2018 Pregnancy Care Guidelines | CRISPR | Ronan O’Rahilly
Retrieved from ‘https://embryology.med.unsw.edu.au/embryology/index.php?title=Template:Main_Page_News&oldid=421379’
Powered by MediaWiki