Template:BGDB Sexual Differentiation - Abnormalities Interactive

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Abnormalities Interactive Component

Attempt the Quiz - Abnormalities  

Here are a few simple Quiz questions that relate to Abnormalities of genital development from the lecture and practical.

1 In a genetic male (44 x XY) who lacks androgen receptors, each of the following will be increased except:


2 The best option below for a child born with ambiguous external genitalia could be:

  46,XX DSD a female pseudohermaphrodite
  46,XY DSD a male pseudohermaphrodite
  Ovotesticular DSD
  someone with Klinefelter’s syndrome
  any of the above

3 In monosomy XO (Turner’s syndrome):

  the children start normal male development
  the number of germ cells in the gonads starts decreasing after puberty
  the children grow disproportionately tall
  an active gene on a dormant X chromosome may account for the clinical manifestations
  all of the above might occur

4 If 46,XY DSD is due to androgen receptor disorders, then:

  the testes are normal for the most part
  the testosterone and DHT levels are normal
  MDIF is secreted by the Sertoli cells
  the fetus will have female external genitalia without a female genital tract
  all of the above is correct

5 Failure of formation and migration of the primordial germ cells results in:

  Turner’s syndrome
  Klinefelter’s syndrome
  46,XX DSD
  gonadal agenesis
  none of the above

6 Failure of the urethral folds to fuse prenatally would be expected to result in:

  exstrophy of urinary bladder
  horseshoe kidney
  multiple ureters

Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio

Additional Information: genital abnormalities