Template:Anti-Mullerian Hormone Vignette
From Embryology
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Johannes Peter Müller (1801 - 1858) in 1830 was the first to describe the female genital duct that develops as the uterus and vagina, historically named after him as the "Müllerian duct". The current terminology is the "paramesonephric duct".
 Anti-Mullerian Hormone (19p13.3) was first discovered in 1947 by Alfred Jost (1916-1991), a French endocrinologist researcher, he used a rabbit model to identify this hormone as responsible for Müllerian duct (paramesonephric duct) regression during fetal rabbit development. His findings explained several abnormalities of sexual development. This included the "freemartin calf", that acquires AMH from a male twin in utero generating an infertile female with masculinized behavior and non-functioning ovaries. Pubmed: Alfred Jost (author) |
