Template:Anderson2016 table2

Table 2. Summary of Timing (Post Fertilization) of Susceptibility to a Drug-Induced Malformation

Lesion	Start of Susceptibility to Malformation	End of Susceptibility to Malformation
Interatrial communications
Oval fossa defect	6 weeks (E13.5)	Term
Sinus venosus defect	8 weeks	12 weeks
Coronary sinus defect	8 weeks	Term
Vestibular defect	7 weeks	8 weeks
Ventricular Septal Defect
Muscular	8 weeks	Difficult to predict
Perimembranous	6 weeks	8 weeks
Doubly committed	7 weeks	8 weeks
Atrioventricular Septal Defect
Ostium primum	5 weeks	6 weeks
“Complete”	5 weeks	6 weeks
Aortic coarctation
With VSD	5 weeks	8 weeks
With intact ventricular septum	8 weeks	Term
Double Outlet Right Ventricle	6 weeks	8 weeks
Transposition of Great Arteries	6 weeks	8 weeks
Ebstein’s malformation	6 weeks	8 weeks
Hypoplastic left heart syndrome
With mitral atresia	5 weeks	8 weeks
With mitral stenosis	8 weeks	Term
Pulmonary atresia
With VSD	6 weeks	8 weeks
With intact ventricular septum	8 weeks	Term
Other
Functionally single ventricle	5 weeks	6 weeks
Tetralogy of Fallot	7 weeks	8 weeks
Totally anomalous pulmonary venous return	8 weeks	12 weeks
Tricuspid atresia	5 weeks	6 weeks
Common arterial trunk	5 weeks	7 weeks
Bicuspid aortic valve	6 weeks	Term
Notes
For approximate clinical Gestational Age GA add 2 weeks; number in brackets is mouse equivalent. Data Reference			Links: heart | abnormal development | timeline | Category:Timeline

Table 2. Summary of Timing (Post Fertilization) of Cardiac Susceptibility to a Drug-Induced Malformation
Lesion	Start of Susceptibility to Malformation	End of Susceptibility to Malformation
Interatrial communications
Oval fossa defect	6 weeks (E13.5)	Term
Sinus venosus defect	8 weeks	12 weeks
Coronary sinus defect	8 weeks	Term
Vestibular defect	7 weeks	8 weeks
Ventricular Septal Defect
Muscular	8 weeks	Difficult to predict
Perimembranous	6 weeks	8 weeks
Doubly committed	7 weeks	8 weeks
Atrioventricular Septal Defect
Ostium primum	5 weeks	6 weeks
“Complete”	5 weeks	6 weeks
Aortic coarctation
With VSD	5 weeks	8 weeks
With intact ventricular septum	8 weeks	Term
Double Outlet Right Ventricle	6 weeks	8 weeks
Transposition of Great Arteries	6 weeks	8 weeks
Ebstein’s malformation	6 weeks	8 weeks
Hypoplastic left heart syndrome
With mitral atresia	5 weeks	8 weeks
With mitral stenosis	8 weeks	Term
Pulmonary atresia
With VSD	6 weeks	8 weeks
With intact ventricular septum	8 weeks	Term
Other
Functionally single ventricle	5 weeks	6 weeks
Tetralogy of Fallot	7 weeks	8 weeks
Totally anomalous pulmonary venous return	8 weeks	12 weeks
Tricuspid atresia	5 weeks	6 weeks
Common arterial trunk	5 weeks	7 weeks
Bicuspid aortic valve	6 weeks	Term
Notes: For approximate clinical Gestational Age GA add 2 weeks; number in brackets is mouse equivalent. Reference: Anderson RH. Teratogenecity in the setting of cardiac development and maldevelopment. (2016)