Talk:Rat Development Stages: Difference between revisions

From Embryology
No edit summary
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Added Stage info to original Witschi Rat Stages==
=== Witschi Rat Stages===
:{{Template:Rat}}
{| class="prettytable"
{| class="prettytable"
|-bgcolor="DDCEF2"
|-bgcolor="DDCEF2"
Line 9: Line 4:


(Witschi)</center>
(Witschi)</center>
| width=80px|  <center>'''Carnegie''' (approx)</center>
| width=80px|  <center>'''Age''' (days)</center>
| width=80px|  <center>'''Age''' (days)</center>
| width=100px| <center>'''Size''' (mm)</center>
| width=100px| <center>'''Size''' (mm)</center>
Line 14: Line 10:


|-
|-
| colspan="4" | <center>'''Cleavage and Blastula'''</center>
| colspan="5" | <center>'''Cleavage and Blastula'''</center>


|-
|-
| 1
| 1
| 1
| 1
| 1
Line 24: Line 21:
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 2
| 2
|
| 2
| 2
| 0.08 x 0.06
| 0.08 x 0.06
Line 30: Line 28:
|-
|-
| 3
| 3
|
| 3
| 3
| 0.08 x 0.05
| 0.08 x 0.05
Line 36: Line 35:
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 4
| 4
| 3.5
|
| 3.25
|  
|  
| 8-12 cells (in oviduct)
| 8-12 cells (in oviduct)
Line 42: Line 42:
|-
|-
| 5
| 5
| 3.25
| 2
| 3.5
| 0.08 x 0.04
| 0.08 x 0.04
| Morula (in uterus)
| Morula (in uterus)
Line 48: Line 49:
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 6
| 6
|
| 4
| 4
| (0.08 x 0.03)
| (0.08 x 0.03)
Line 54: Line 56:
|-
|-
| 7
| 7
| 3
| 5
| 5
| (0.12 x 0.05)
| (0.12 x 0.05)
Line 59: Line 62:


|-bgcolor="DDCEF2"
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Gastrula'''</center>
| colspan="5" | <center>'''Gastrula'''</center>


|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 8
| 8
| 4
| 6
| 6
| (0.28 x 0.07)
| (0.28 x 0.07)
Line 69: Line 73:
|-
|-
| 9
| 9
|
| 6.75
| 6.75
|  
|  
Line 75: Line 80:
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 10
| 10
| 5
| 7.25
| 7.25
| (0.3 x 0.1)
| (0.3 x 0.1)
Line 81: Line 87:
|-
|-
| 11
| 11
|
| 7.75
| 7.75
| (0.5 x 0.1)
| (0.5 x 0.1)
Line 86: Line 93:


|-bgcolor="DDCEF2"
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Primitive Streak'''</center>
| colspan="5" | <center>'''Primitive Streak'''</center>


|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 12
| 12
| 6
| 8.5
| 8.5
| (1.04 x 0.26)
| (1.04 x 0.26)
Line 95: Line 103:


|-bgcolor="DDCEF2"
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Neurula'''</center>
| colspan="5" | <center>'''Neurula'''</center>


|-
|-
| 13
| 13
| 7
| 9
| 9
| 1.0
| 1.0
Line 105: Line 114:
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
| 14
| 14
|
| 9.5
| 9.5
| 1.5
| 1.5
| Somites 1-4 (occipital); pendant with 3 cavities: ectochorionic cyst, exocoelom, and amniotic cavity; ectochorionic cyst collapsing; allantoic stalk projects into exocoelom; embryo bent dorsally
| Somites 1-4 (occipital); pendant with 3 cavities: ectochorionic cyst, exocoelom, and amniotic cavity; ectochorionic cyst collapsing; allantoic stalk projects into exocoelom; embryo bent dorsally
|-
| 15
| 10
| 2
| Somites 5-12 (cervical); 1st visceral arch; ectochorionic cyst fused with ectoplacenta and with allantoic stalk; regression of peripheral (distal) yolk sac and trophectoderm (diplotrophoblast); Reichert's membrane; gonia in endoderm; embryo bent dorsally
|-bgcolor="FAF5FF"
| 16
| 10.5
| 2.4
| Somites 13-20 (upper thoracic); 2 visceral arches; disc and yolk sac placentas; appendicular folds; embryo reverses, curves ventrally
|-
| 17
| 11
| 3.3
| Somites 21-25 (lower thoracic); yolk stalk closes at level of 15th somite; primary gonia in mesentery; primitive streak disappears; tail bud becomes organized; arm and leg buds recognizable
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Tail Bud Embryo'''</center>
|-bgcolor="FAF5FF"
| 18
| 11.5
| 3.8
| Somites 26-28 (upper lumbar); 3 visceral arches; arm buds recognizable
|-
| 19
| 11.75
| 4.2
| Somites 29-31 (lower lumbar); visceral arches I-IV; cervical folds; appendicular folds and buds
|-bgcolor="FAF5FF"
| 20
| 11.875
| 5
| Somites 32-33 (upper sacral)
|-
| 21
| 12
| 5.1
| Somites 34-35 (lower sacral); deep cervical sinuses
|-bgcolor="FAF5FF"
| 22
| 12.125
| 5.2
| Somite 36 (1st caudal); olfactory pits
|-
| 23
| 12.25
| 5.6
| Somites 37-38 (caudal); start of umbilical herniation
|-bgcolor="FAF5FF"
| 24
| 12.375
| 6
| Somites 39-40 (caudal)
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Complete Embryo'''</center>
|-
| 25
| 12.5
| 6.2
| Somites 41-42 (caudal); occipital somites dispersing; 4 visceral arches; deep cervical sinuses; arm buds at somite levels 8-14, about as high as long; leg buds at somite levels 28-31, smaller; body forms a spiral of about 11/2 turns, the left face and trunk applied to yolk sac, the right side turned toward placenta; tail and allantoic stalk rise to the placenta
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Metamorphosing Embryo'''</center>
|-bgcolor="FAF5FF"
| 26
| 12.75
| 7
| Somites 43-45 (caudal); mandibular, maxillary, and frontonasal processes; cervical sinuses closing; mammary welts; differentiaion of handplates; arm buds vascularized, brachial nerves entering; beginning of umbilical hernia
|-
| 27
| 13
| 8
| Somites 46-48 (caudal); prominent facial processes and clefts; nose-snout projecting; cervical sinuses closed; primordia of mammary glands; round handplates and footplates; larger umbilical hernia
|-bgcolor="FAF5FF"
| 28
| 13.5
| 8.5
| Somites 49-51 (caudal); 1st visceral cleft transforms into external ear duct; precartilaginous condensations in handplates
|-
| 29
| 14
| 9.5
| Somites 52-55 (caudal); auricular hillocks on visceral arches I and II
|-bgcolor="FAF5FF"
| 30
| 14.5
| 10.5
| Somites 56-60 (caudal); body uncoils; mandibular precartilage; nearly round opening of external ear duct; pleuroperitoneal canal has become very narrow
|-
| 31
| 15
| 12
| Somites 61-63 (caudal); facial clefts closed; pleuroperitoneal canal closed; complete diaphragm
|-bgcolor="FAF5FF"
| 32
| 15.5
| 14.2
| Somite 64 (caudal); pinna turns forward; maximal size of umbilical hernia
|-
| 33
| 16
| 15.5
| Somite 65 (usually this is last caudal); snout lifts off chest; last stage of metamorphosis
|-bgcolor="DDCEF2"
| colspan="4" | <center>'''Fetus'''</center>
|-bgcolor="FAF5FF"
| 34
| 17-18
| 16-20
&nbsp;
| 1st fetal stage: rapid growth of eyelids (eyes entirely covered at end of 18th day); palate complete; pinna covers ear duct; umbilical hernia withdraws
|-
| 35
ante-natal
| 19-22
| 20-40
&nbsp;
| 2nd fetal stage: sealed eyelids; fetal membranes and placentas reach peak of development; tail grows to 10mm;
[[Neural System Development]] Pathways to the supraoptic nucleus from the brainstem and the main olfactory bulb - on the expected day of parturition, but before birth, projections from the organum vasculosum of the lamina terminalis to the supraoptic nucleus became significantly activated. [http://www.ncbi.nlm.nih.gov/pubmed/11113350 PMID: 11113350]
'''Birth''' occurs (22nd day in rat, 19th day in mouse)
|-
| 35
post-natal
| 1-16 post-partum
| 40-1001
| After birth, fetus becomes a breathing and suckling nestling2<nowiki>; during 1st 16 days (22 to 38 days total age), eyelids remain sealed and external ear ducts plugged with periderm</nowiki>
|-bgcolor="FAF5FF"
| 36
post-natal
| 17+ post-partum
| 100+1
| Periderm seals of ears and eyelids vanish; active feeding begins within next 3 days and weaning after 1 week (total weaning age, 45-48 days for rats and mice)
|}
'''&nbsp;'''
'''<nowiki>* Age (days)-</nowiki>''' days after fertilization
'''<nowiki>* Size (mm)-</nowiki>''' largest and smallest dimensions
=== Table Data ===
The main table data is modified from <ref name="Witschi 1962">Witschi, E. (1962) Development: Rat. In: '''Growth Including Reproduction and Morphological Development.''' Altman, P. L. , and D. S. Dittmer, ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.</ref> and other sources as listed within the table.
==Species Stages Comparison ==
The table below gives an approximate comparison of human, mouse and rat embryos based upon Carnegie staging.
{| class="prettytable"
|-bgcolor= "lightsteelblue"
| Species
| '''Stage'''
| <center>'''9''' </center>
| <center>'''10''' </center>
| <center>'''11''' </center>
| <center>'''12''' </center>
| <center>'''13''' </center>
| <center>'''14''' </center>
| <center>'''15''' </center>
| <center>'''16''' </center>
| <center>'''17''' </center>
| <center>'''18''' </center>
| <center>'''19''' </center>
| <center>'''20''' </center>
| <center>'''21''' </center>
| <center>'''22''' </center>
| <center>'''23''' </center>
|-
| [[Embryonic Development|Human]] <ref><pubmed>400868</pubmed></ref>
| Days
| 20
| 22
| 24
| 28
| 30
| 33
| 36
| 40
| 42
| 44
| 48
| 52
| 54
| 55
| 58
|-
| [[Mouse Development|Mouse]] <ref name="The House Mouse">The House Mouse: Atlas of Mouse Development''' by Theiler Springer-Verlag, NY (1972, 1989). | [http://genex.hgu.mrc.ac.uk/Atlas/Theiler_book_download.html online book]</ref>
| Days
| 9
| 9.5
| 10
| 10.5
| 11
| 11.5
| 12
| 12.5
| 13
| 13.5
| 14
| 14.5
| 15
| 15.5
| 16
|-
| [[Rat Development|Rat]] <ref name="Witschi 1962" />
| Days
| 10.5
| 11
| 11.5
| 12
| 12.5
| 13
| 13.5
| 14
| 14.5
| 15
| 15.5
| 16
| 16.5
| 17
| 17.5
|}
|}
==References==
<references/>
----
{{Template:Animals}}
{{Template:Glossary}}
{{Template:Footer}}
[[Category:Rat]]

Latest revision as of 13:22, 7 September 2011

Standard Stages (Witschi)
Carnegie (approx)
Age (days)
Size (mm)
Identification of Stages
Cleavage and Blastula
1 1 1 0.07 1 cell (in oviduct)
2 2 0.08 x 0.06 2 cells (in oviduct)
3 3 0.08 x 0.05 4 cells (in oviduct)
4 3.25 8-12 cells (in oviduct)
5 2 3.5 0.08 x 0.04 Morula (in uterus)
6 4 (0.08 x 0.03) Early blastocyst (in uterus)
7 3 5 (0.12 x 0.05) Free blastocyst (in uterus)
Gastrula
8 4 6 (0.28 x 0.07) Implanting blastocyst, with trophoblastic cone and inner cell mass; outgrowth of endoderm (hypoblast)
9 6.75 Diplotrophoblast; inner cell mass (pendant), covered with endoderm
10 5 7.25 (0.3 x 0.1) Near complete implantation; pendant begins differentiation into embryonic and extra-embryonic parts
11 7.75 (0.5 x 0.1) Completion of implantation; primary amniotic cyst; ectoplacental cone
Primitive Streak
12 6 8.5 (1.04 x 0.26) Connecting ectochorionic and amniotic cavities; rudiments of amniotic folds; primitive streak; start of 3rd layer formation; blastemas of heart and pericardium
Neurula
13 7 9 1.0 Presomite neurula; fusion of chorio-amniotic folds, chorio-amniotic stalk; neural plate; embryo bent dorsally; bud of allantoic stalk
14 9.5 1.5 Somites 1-4 (occipital); pendant with 3 cavities: ectochorionic cyst, exocoelom, and amniotic cavity; ectochorionic cyst collapsing; allantoic stalk projects into exocoelom; embryo bent dorsally
Retrieved from ‘https://embryology.med.unsw.edu.au/embryology/index.php?title=Talk:Rat_Development_Stages&oldid=67722’
Powered by MediaWiki