Talk:Kyoto Collection
Collection Overview
(Last Updated - April 7, 2014) Specimens 23,813
Stage | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | Embryonic | Fetal |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal | 14 | 16 | 5 | 25 | 44 | 298 | 745 | 2133 | 1569 | 2653 | 2621 | 2697 | 2417 | 2393 | 1620 | 1101 | 909 | 21260 | 920 |
Abnormal | 0 | 0 | 1 | 2 | 4 | 9 | 42 | 69 | 40 | 167 | 236 | 186 | 131 | 265 | 260 | 114 | 50 | 1576 | 54 |
Total | 14 | 16 | 6 | 27 | 48 | 307 | 787 | 2202 | 1609 | 2820 | 2857 | 2883 | 2548 | 2658 | 1880 | 1215 | 959 | 22836 | 974 |
Stage | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | Embryonic | Fetal |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal | 14 | 16 | 5 | 25 | 44 | 298 | 745 | 2133 | 1569 | 2653 | 2621 | 2697 | 2417 | 2393 | 1620 | 1101 | 909 | 21260 | 920 |
Abnormal | 0 | 0 | 1 | 2 | 4 | 9 | 42 | 69 | 40 | 167 | 236 | 186 | 131 | 265 | 260 | 114 | 50 | 1576 | 54 |
Total | 14 | 16 | 6 | 27 | 48 | 307 | 787 | 2202 | 1609 | 2820 | 2857 | 2883 | 2548 | 2658 | 1880 | 1215 | 959 | 22836 | 974 |
2014
A detailed comparison of mouse and human cardiac development
Pediatr Res. 2014 Dec;76(6):500-7. doi: 10.1038/pr.2014.128. Epub 2014 Aug 28.
Krishnan A1, Samtani R2, Dhanantwari P3, Lee E4, Yamada S5, Shiota K5, Donofrio MT6, Leatherbury L1, Lo CW7.
Abstract
BACKGROUND: Mouse mutants are used to model human congenital cardiovascular disease. Few studies exist comparing normal cardiovascular development in mice vs. humans. We carried out a systematic comparative analysis of mouse and human fetal cardiovascular development. METHODS: Episcopic fluorescence image capture (EFIC) was performed on 66 wild-type mouse embryos from embryonic day (E) 9.5 to birth; 2-dimensional and 3-dimensional datasets were compared with EFIC and magnetic resonance images from a study of 52 human fetuses (Carnegie stage 13-23). RESULTS: Time course of atrial, ventricular, and outflow septation were outlined and followed a similar sequence in both species. Bilateral venae cavae and prominent atrial appendages were seen in the mouse fetus; in human fetuses, atrial appendages were small, and a single right superior vena cava was present. In contrast to humans with separate pulmonary vein orifices, a pulmonary venous confluence with one orifice enters the left atrium in mice. CONCLUSION: The cardiac developmental sequences observed in mouse and human fetuses are comparable, with minor differences in atrial and venous morphology. These comparisons of mouse and human cardiac development strongly support that mouse morphogenesis is a good model for human development. PMID 25167202
Search: Yamada S
Variabilities in prenatal development of orofacial system
Anat Anz. 1991;172(2):97-107.
Tanaka O.
Abstract
Reliable information on embryonic and fetal development of the human oro-facial system is meager. Much of the data available at present is not entirely reliable, because it was derived from a small number of specimens. An embryological approach with human materials is important for establishing a normal standard of development including individual variabilities as well as clarifying the embryogenesis and etiology of defective development (Nishimura et al. 1977). It is important in human craniofacial embryology to know the variabilities, that is, individual differences in developmental phenomena of the oro-facial region during human prenatal life. In recent times the importance of morphologic investigations of human development has received less emphasis. Yet, without thorough knowledge of the basic facts of prenatal human development, erroneous assumptions can be made in more dynamic approaches and lead investigators astray. Knowledge of prenatal development of human orofacial structures and some of their deviations will therefore be welcomed by many basic scientists and clinicians in the field of facial clefts and other craniofacial malformations. The author was engaged in the collection and systematic study of human embryos and fetuses with Dr. Hideo Nishimura, Emeritus Professor of Kyoto University, Kyoto, Japan, and has been studying the normal and abnormal development during prenatal life. Several results obtained from the study of a large number of specimens are presented laying stress on the orofacial development.
PMID 2048747