Talk:Gastrointestinal Tract - Mesentery Development
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Cite this page: Hill, M.A. (2024, April 28) Embryology Gastrointestinal Tract - Mesentery Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Gastrointestinal_Tract_-_Mesentery_Development |
2020
2019
Hikspoors JPJM, Kruepunga N, Mommen GMC, Peeters JPWU, Hülsman CJM, Eleonore Köhler S & Lamers WH. (2018). The development of the dorsal mesentery in human embryos and fetuses. Semin. Cell Dev. Biol. , , . PMID: 30142441 DOI.
The development of the dorsal mesentery in human embryos and fetuses
The vertebrate intestine has a continuous dorsal mesentery between pharynx and anus that facilitates intestinal mobility. Based on width and fate the dorsal mesentery can be subdivided into that of the caudal foregut, midgut, and hindgut. The dorsal mesentery of stomach and duodenum is wide and topographically complex due to strong and asymmetric growth of the stomach. The associated formation of the lesser sac partitions the dorsal mesentery into the right-sided "caval fold" that serves as conduit for the inferior caval vein and the left-sided mesogastrium. The thin dorsal mesentery of the midgut originates between the base of the superior and inferior mesenteric arteries, and follows the transient increase in intestinal growth that results in small-intestinal looping, intestinal herniation and, subsequently, return. The following fixation of a large portion of the abdominal dorsal mesentery to the dorsal peritoneal wall by adhesion and fusion is only seen in primates and is often incomplete. Adhesion and fusion of mesothelial surfaces in the lesser pelvis results in the formation of the "mesorectum". Whether Toldt's and Denonvilliers' "fasciae of fusion" identify the location of the original mesothelial surfaces or, alternatively, represent the effects of postnatal wear and tear due to intestinal motility and intra-abdominal pressure changes, remains to be shown. "Malrotations" are characterized by growth defects of the intestinal loops with an ischemic origin and a narrow mesenteric root due to insufficient adhesion and fusion. Copyright © 2018 Elsevier Ltd. All rights reserved. KEYWORDS: (Mal-)rotation of gut; Caval fold; Denonvilliers’ fascia; Lesser sac; Mesogastrium; Slide-and-stack concept of intestinal return; Toldt’s fascia
DOI: 10.1016/j.semcdb.2018.08.009
2018
Development of mesenteric tissues
Semin Cell Dev Biol. 2018 Oct 19. pii: S1084-9521(18)30234-9. doi: 10.1016/j.semcdb.2018.10.005. [Epub ahead of print]
Byrnes KG1, McDermott K2, Coffey JC3.
Abstract
Mesothelial, neurovascular, lymphatic, adipose and mesenchymal tissues make up the mesentery. These tissues are pathobiologically important for numerous reasons. Collectively, they form a continuous, discrete and substantive organ. Additionally, they maintain abdominal digestive organs in position and in continuity with other systems. Furthermore, as they occupy a central position, they mediate transmission of signals between the abdominal digestive system and the remainder of the body. Despite this physiologic centrality, mesenteric tissue development has received little investigatory focus. However, recent advances in our understanding of anatomy demonstrate continuity between all mesenteric tissues, thereby linking previously unrelated studies. In this review, we examine the development of mesenteric tissue in normality and in the setting of congenital abnormalities. PMID: 30347243 DOI: 10.1016/j.semcdb.2018.10.005
Anatomy of the mesentery: Current understanding and mechanisms of attachment
Semin Cell Dev Biol. 2018 Oct 15. pii: S1084-9521(18)30205-2. doi: 10.1016/j.semcdb.2018.10.004. [Epub ahead of print]
Byrnes KG1, Walsh D2, Dockery P3, McDermott K4, Coffey JC5.
Abstract
An understanding of the anatomy of the mesentery is necessary to undertake any appraisal of the literature on its development. The mesentery is the collection of tissues that maintain all abdominal digestive organs in position and connection with the rest of the body. Therefore, it is also necessary to detail the exact mechanisms that maintain the mesentery in position. We explore these mechanisms, including the supportive functions of structures such as Toldt's fascia, the peritoneal reflection, and vascular connections, in this article. KEYWORDS: Anatomy; Attachment; Fascia; Mesentery; Peritoneum PMID: 30316831 DOI: 10.1016/j.semcdb.2018.10.004
