Talk:Fertilization

References

Sperm head binding to epithelium of the oviduct isthmus is not an essential preliminary to mammalian fertilization - review

Zygote. 2010 Jul 21:1-5.

Hunter RH.

Institute for Reproductive Medicine, Hannover Veterinary University, Bünteweg 15, D-30559 Hannover, Germany. Abstract SummaryIn endeavouring to understand the nature of sperm-oviduct interactions in mammals, attention was focused on experimental models in which fertilization can occur without a preliminary phase of sperm head binding to the isthmus epithelium. The ovarian endocrine milieu imposed on the oviduct tissues plays an important role in the binding phenomenon, although less so after the time of ovulation. Nonetheless, a sperm suspension introduced into the peritoneal cavity or surgical insemination directly into the oviduct ampulla before ovulation can result in fertilization, as can a surgical model in which the isthmus has been resected and the remaining portions of the duct reanastomosed. Mating or artificial insemination after ovulation in pigs permits rapid sperm transport to the site of fertilization, and the frequency of polyspermic penetration increases with the post-ovulatory age of eggs.Strategies underlying sperm binding were considered, especially in terms of preovulatory sperm storage and suppression of full membranous maturation. These, in turn, raised the problem of how sperm binding in vitro to oviduct cells from prepuberal animals or to cells harvested during the luteal phase of the estrous cycle, or to cells from the ampulla or even the tracheal epithelium, can act to regulate sperm storage and maturation with precision. In an evolutionary perspective, preovulatory binding of diverse populations of cells to the endosalpinx may have developed as a form of fine tuning to assist in sperm selection, to synchronize completion of capacitation with the events of ovulation, and to promote monospermic fertilization by a controlled release of competent gametes.

PMID: 20663263 http://www.ncbi.nlm.nih.gov/pubmed/20663263

Sperm binding to the zona pellucida is not sufficient to induce acrosome exocytosis.

Baibakov B, Gauthier L, Talbot P, Rankin TL, Dean J. Development. 2007 Mar;134(5):933-43. PMID: 17293534

IJDB

Vol. 52 Nos. 5/6 (2008) Fertilization

http://www.ijdb.ehu.es/web/contents.php?vol=52&issue=5-6

inactive X chromosome

Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome. Chadwick BP, Willard HF. J Cell Biol. 2002 Jun 24;157(7):1113-23. Epub 2002 Jun 24. PMID: 12082075 \ JCB

Histone modifications and nuclear architecture: a review.

Bártová E, Krejcí J, Harnicarová A, Galiová G, Kozubek S.

J Histochem Cytochem. 2008 Aug;56(8):711-21. Epub 2008 May 12. Review.PMID: 18474937