Talk:Book - Manual of Human Embryology 18-8

Florence Rena Sabin (1871-1953)

• The Florence R. Sabin Papers
• Biographical Information
  • "Sabin stayed on the faculty at Johns Hopkins until 1925, and during that time distinguished herself both as a researcher and a teacher. She did important work on the origins of the lymphatic system, demonstrating (by injecting colored substances into the lymphatic channels) that its structures were formed from the embryo's veins rather than from other tissues, as other researchers believed. She also investigated the origins of blood vessels, blood cells, and connective tissue. To do this, she perfected the technique of supravital staining, which allowed the study of the living cells. In 1924, she became the first woman president of the American Association of Anatomists, and the next year, the first woman elected to membership in the National Academy of Sciences."

Back to The Development of the Lymphatic System

Development of the Lymphatics In the Embryos and Fetuses of the Mall Collection

Table Showing Development of the Lymphatics In the Embryos and Fetuses of the Mall Collection
(Of the measurements, the first figure is the craniocaudal diameter, the second the transverse. and the third the dorsoventral.)
Embryo length mm	Carnegie No.	Direction of section	Jugular lymph-sac		Other lymph-sac
			Size in mm	Condition	Cisterna chuli	Sacculus Xretroperitonealis	Sacculus posterior
8	397	Transverse	0.3 x 0.10	Prelymphatic plexus of veins.
9	163	Transverse	0.36 x .014	Prelymphatic plexus of veins.
10.5	109	Transverse	0.7 x 0.28	Symmetrical sacs, empty, possible valves.
11	353	Frontal	1.2	Sac full of blood. Capillary plexus along the v. jugularis. Valve not open. Extension of jugular sac along v. ulnaris.
12.5	317	Frontal	1.5	Long sac has replaced previous plexus of veins. Valve.
14	144	Sagittal	1.5	Empty sac, beginning of bridging.
15	350	Frontal		Sac very small.
15	423	Transverse	0.9	Sac very small.
16	409	Transverse		Large sac with the anlages of the ductus thoracicus and ductus lymphaticus dexter.
17	106	Transverse		Sac very small.
17	296	Frontal	1.5	Large sac. Open valve. Small extension of the sac along the v. ulnaris primitiva
16	74	Transverse		Jugular sac with no extension along the v. ulnaris.
20	22	Transverse	1.6	Sac wider. pierced by nerve. First Vessels from the sac to the skln.	Plexus of capillaries along the anastomosis of the v. renalis.
20	128	Frontal	0.75	Sac very small.			Capillaries along the v. ischiadiea.
23	382	Sagittal	2 x 1	Large sac with valves.	Present.	Present.
24	6	Transverse		Large sac.	Present.	Present.	Present.
30	56	Frontal	5 x 3.6	Maximum size. Beginning formation of lymph-glands in the saccus jugulo-subclavius.	Present; thoracic duct complete.	Present.	4.6 x 1, with beginning lymph-node.
46	95	Sagittal	3.75 x 1.5	Sac with few lymph-nodes.	Not found.	Present. no lymph-nodes.	2.5 x 0.75
50	96	Sagittal	4 x 1.5	Sac turning into lymph-nodes.	Not found.	Present. no lymph-nodes.	3 x 1.75
50	84	Transverse	3 x 1.5	Many follicles.	1.2	1.6 x 1	1.75 x 2
50	224	Sagittal	4 x 1.75	Five bridges throughout.	Damaged.	Damaged.	2 x 1
80	172	Transverse	1.75 x 2 not complete	A chain of lymph-nodes.	Surrounded by lymph-nodes.	Mass of lymph-nodes	Sac with lymph-nodes 2.8 x 2 x 3.5