Talk:2018 Group Project 1: Difference between revisions
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In “current research” you have copied and pasted the introduction from the article cited. This definitely needs to be put into your own words, and maybe simplified as currently it is quite difficult to understand. | In “current research” you have copied and pasted the introduction from the article cited. This definitely needs to be put into your own words, and maybe simplified as currently it is quite difficult to understand. | ||
This project is good because it appears to have a decent number of headings that they are going to address that covers all the aspects of the embryonic adrenal medulla. It has a very detailed history that the reader can easily follow, as well as a simple student drawn image which is good to see on the page. The developmental time course is brief and addresses what it needs to. There is also good information on the tissue structure and function, as well as on its role and the factors involved in its development. The project is also good in including animal model and current research examples. The two chalk diagrams are very detailed and easy to understand. | |||
The introduction has not been written yet, but that’s alright as it can be saved for the end of the project. Embryonic origin still needs to be written about, and should have a lot of information, as well as the abnormalities of development. The referencing is confusing at the bottom of each section and there should be more references in the reference list. There should also be images that aren’t student drawn and there should be more of them. The glossary also needs to be updated. | |||
In terms of improvements, maybe an educational video could be added about the origin of the adrenal medulla or the developmental time course. A list describing what the acronyms mean could also be really helpful to the reader. The arrangement of the images could be neater but that is saved for the end of the project. | |||
Overall. I think this is a really good project that shows a lot of effort and work being done as it is informative but easy to follow. | |||
=Group 1 discussion:= | =Group 1 discussion:= |
Revision as of 13:15, 7 October 2018
Adrenal Medulla Development
Projects 2018: 1 Adrenal Medulla | 3 Melanocytes | 4 Cardiac | 5 Dorsal Root Ganglion |
Project Pages are currently being updated (notice removed when completed)
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Peer Reviews (Lab 10)
Z5229549 (talk) 16:07, 6 October 2018 (AEST) Content on a whole was relatively smooth to read, not too much technical jargon that is often seen in more off-putting texts. The inclusion of self-drawn images brings a refreshing colour to the overall page, and seem rather accurate too, though the arrangement and positioning of the images and text could use some readjustment.
However, there are still some headers that are lacking content, presumably still under editing and would be up soon. It also would be to some diagrams of the several experiments mentioned under animal models instead of just a large block of text.
Overall, aside from several empty headers, the ones currently there more or less have the content nailed down, though several polishings and edits could be made.
Z5229185 (talk) 17:45, 4 October 2018 (AEST) I feel that the introduction sounded a bit off as referring to neural crest as a term seems rather inaccurate. A good history of the neural crest cells was provided and it is quite detailed (in fact it may be too detailed as it seems really long).
I really like the hand drawing of the neural crest but I feel that it would look much better if you shifted the image to the right rather than let it take up the whole space.
The content was pretty easy to follow and digest, so good job on that! You might want to take note on some errors in punctuation throughout the wiki page but since its just a draft, it isn't that big of an issue for now.
The animal models section was really detailed and quite well written but the references need to be edited properly in the right format. I'm also a little confused as to why the picture of the "cascade of cathecholamine synthesis" is found right beside the Animal model section, you may want to adjust this!
There are a few references present at the end of the page, but I assume this is because the other references have not been formatted properly yet.
Overall good job with the page so far! I can see that the flow is some what smooth already (except for the empty sections) but just take note that there are still a few tweaks to be done with the referencing and placement of images!
- Perhaps describe the neural crest as a “structure” instead of a term. Great use of the student-drawn image as a guide! Overall, good simplified history.
In the normal structure and function region; good but rather brief discussion of the physiology and structure. perhaps a little bit more, and maybe an image- unless you merge it with the related anatomy component. Really love the adult adrenal gland and the effort behind it. Only complaint would be that perhaps it would have been good to have the regions of the kidney (medulla, cortex etc).
The description of the role of the adrenal medulla is very well-written; concise and seemingly accurate. Perhaps include the proper dot point structure instead of the >. The image drawn illustrating the cascade of catecholamine synthesis is also very good and I personally found it to be a helpful guide. However, it needs to be edited and correctly formatted for the webpage.
The first two sentences of the animal models section may be combined into one. Proof-reading required eg. as explained above ‘nueral’! Who is Ahonen- Is an in-text reference needed here? Perhaps this paragraph belongs in the current research section as the animal used hasn’t been mentioned. Please review this bit as the information provided is good and relevant but maybe in the wrong section.
In the current research section, the second sentence says ‘we generated’ … who are you referring to? The information here seems correct but was also quite advanced with numerous terms that I couldn’t understand- however it shows great research so well done!
Overall, great work guys! Keep it up and move along with the project consistently! Perhaps include some images from the experiments you’ve described and some more high-tech images- although the ones you have drawn are also excellent! :) **
The beginning introduction is good and very detailed which is excellent as it shows adequate research has been applied but it may be too in depth as the project pertains to the adrenal medulla. But after reading it all it transitions nicely into the project so I don't mind all of the details that much. The information is organized and is well constructed in the first section of this project I like the time frames and each description under each, maybe use more than one reference for the intro so it is not all from one source. other than that the intro is really good.
For the developmental adult section, it is either not researched or not started, I would just remove it as the rest of the project is put together and the adult function is not super important. Also, the developmental time course would be really cool to have to see the steps involved in the creation of the medulla, if not added not a big deal.
The hand drawn figures are really nice add a certain flare to the project which i think is sweet.
Other than that minor edits need to be made and this project is polished, some sections need to be researched more as there are still two weeks left until it is assessed, so plenty of time to polish.
Group Project 1:
The History section is very detailed - more weight on the history of neural crest discovery related to the adrenal medulla specifically would be appreciated, as this is your topic, but I do think that it is good that you have maintained a focus on neural crest.
I think your section on genes and transcription factors is well described - I like that you have given a mouse model example. I presume the links to the sites will be added as proper references later. I also think the image of the cascade of catecholamine synthesis is helpful for those interested in the pathway, though its location is currently too far away from this section on the page. However, this is a minor issue and something that might be tidied up nearer the end of the assignment.
You currently don’t have any abnormalities/abnormal development information. It would be nice to see some example here such as Congenital Adrenal Hyperplasia.
In “current research” you have copied and pasted the introduction from the article cited. This definitely needs to be put into your own words, and maybe simplified as currently it is quite difficult to understand.
This project is good because it appears to have a decent number of headings that they are going to address that covers all the aspects of the embryonic adrenal medulla. It has a very detailed history that the reader can easily follow, as well as a simple student drawn image which is good to see on the page. The developmental time course is brief and addresses what it needs to. There is also good information on the tissue structure and function, as well as on its role and the factors involved in its development. The project is also good in including animal model and current research examples. The two chalk diagrams are very detailed and easy to understand.
The introduction has not been written yet, but that’s alright as it can be saved for the end of the project. Embryonic origin still needs to be written about, and should have a lot of information, as well as the abnormalities of development. The referencing is confusing at the bottom of each section and there should be more references in the reference list. There should also be images that aren’t student drawn and there should be more of them. The glossary also needs to be updated.
In terms of improvements, maybe an educational video could be added about the origin of the adrenal medulla or the developmental time course. A list describing what the acronyms mean could also be really helpful to the reader. The arrangement of the images could be neater but that is saved for the end of the project.
Overall. I think this is a really good project that shows a lot of effort and work being done as it is informative but easy to follow.
Group 1 discussion:
introduction
Z5014972 (talk) 12:47, 14 August 2018 (AEST)z5014972
A really good review article can be found here: https://link.springer.com/article/10.1007%2Fs12022-009-9070-6 as well as here: https://www.jstage.jst.go.jp/article/jvms/66/6/66_6_635/_pdf ( Z5113627 )
history
https://www.ncbi.nlm.nih.gov/books/NBK10065/
z5091101Z5091101 (talk) 21:01, 25 August 2018 (AEST)
Z5091101 (talk) 17:29, 4 September 2018 (AEST)z5091101Z5091101 (talk) 17:29, 4 September 2018 (AEST)
A paper with some info on discovery/history https://www.ncbi.nlm.nih.gov/pubmed/19179766
Can we please add normal anatomy of the adrenal medulla as a subheading - normal anatomy of adult medulla Was history referring to the history of discovery?
Z5091101 (talk) 11:46, 4 September 2018 (AEST)z5091101Z5091101 (talk) 11:46, 4 September 2018 (AEST)
make a schematic drawing flow diagram outlining briefly history of neural crest
History of endocrine development (add to intro)
Z5091101 (talk) 15:47, 12 September 2018 (AEST)z5091101Z5091101 (talk) 15:47, 12 September 2018 (AEST)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425661/
https://onlinelibrary.wiley.com/doi/full/10.1002/dvdy.21513
Z5091101 (talk) 16:56, 12 September 2018 (AEST)z5091101Z5091101 (talk) 16:56, 12 September 2018 (AEST)
embryonic origins
Z5091101 (talk) 11:46, 4 September 2018 (AEST)z5091101Z5091101 (talk) 11:46, 4 September 2018 (AEST) https://clinicalgate.com/neural-crest/ Want to upload either image - https://clinicalgate.com/neural-crest/ - https://upload.wikimedia.org/wikipedia/commons/3/3d/Figure_43_06_01.jpg
Origin is from neural crest cells; ectoderm
https://link.springer.com/article/10.1007/s12038-008-0098-4
developmental time course
developmental/adult function
tissue/organ structure
The tissue and organ structure of the adrenal medulla should be understood with regard to its specialized function within the sympathetic nervous system.
molecular mechanisms/factors/genes
abnormalities/abnormal development
animal models
https://www.ncbi.nlm.nih.gov/pubmed/21175739
Prenatal adrenal gland development has been described in numerous published reports covering a wide variety of species, including the ox (Katznelson, 1966; Wrobel and Suss, 1999), sheep (Davies, 1950; Wintour et al., 1975; Upadhyay and Zamboni, 1982; Naaman‐Reperant and Durand, 1997; Grino, 2004), swine (Sokolov et al., 2006) and mouse (Waring, 1935; Ikeda et al., 1994; Sass, 1996; Nyska and Maronpot, 1999; Bland et al., 2003; Val et al., 2007). Adrenal gland development also has been extensively described for humans as well (Kolliker, 1879; Minot, 1892; Zuckerkandl, 1912; Wieman, 1920; Ikeda et al., 1981; Langlois et al., 2002; Hanley and Arit, 2006), One‐Humped Camel (Camelus dromedarius)
current research (labs)
glossary
reference list
Z5091101 (talk) 11:40, 14 August 2018 (AEST)
Z5014972 (talk) 11:42, 14 August 2018 (AEST)z5014972
Week 4 researching:
- developmental time course
- developmental/adult function
- tissue/organ structure
Z5112688 (talk) 11:43, 14 August 2018 (AEST)Z5112688
[3]
[4]
- ↑ Mansfield CW, Carr BR, Faye-Petersen OM, Chen D, Xing Y, Rainey WE & Parker CR. (2011). Differential gene expression in the adrenals of normal and anencephalic fetuses and studies focused on the Fras-1-related extracellular matrix protein (FREM2) gene. Reprod Sci , 18, 1146-53. PMID: 22031191 DOI.
- ↑ Yamaguchi-Shima N, Okada S, Shimizu T, Usui D, Nakamura K, Lu L & Yokotani K. (2007). Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats. Eur. J. Pharmacol. , 564, 94-102. PMID: 17350615 DOI.
- ↑ Bronner ME. (2012). Formation and migration of neural crest cells in the vertebrate embryo. Histochem. Cell Biol. , 138, 179-86. PMID: 22820859 DOI.
- ↑ Xing Y, Lerario AM, Rainey W & Hammer GD. (2015). Development of adrenal cortex zonation. Endocrinol. Metab. Clin. North Am. , 44, 243-74. PMID: 26038200 DOI.