Difference between revisions of "Talk:2012 Group Project 3"

From Embryology
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'''1.''' <pubmed>21978088</pubmed>  
 
'''1.''' <pubmed>21978088</pubmed>  
[http://www.ncbi.nlm.nih.gov/pubmed/21978088 Link]
 
 
 
  
 
'''2.''' [http://embryology.med.unsw.edu.au/notes/tongue.htm#17108952 UNSW Embryology Development of Taste]  
 
'''2.''' [http://embryology.med.unsw.edu.au/notes/tongue.htm#17108952 UNSW Embryology Development of Taste]  
 
* This website provides a really great overview of taste developmental timing & overview, tastebuds, receptors, pathways, genes and provides great references for further research - and its a UNSW site!  
 
* This website provides a really great overview of taste developmental timing & overview, tastebuds, receptors, pathways, genes and provides great references for further research - and its a UNSW site!  
 
  
 
'''3.''' [http://www.sciencedaily.com/releases/2006/12/061205214617.htm Researchers Discover Initial Steps In Development Of Taste]  
 
'''3.''' [http://www.sciencedaily.com/releases/2006/12/061205214617.htm Researchers Discover Initial Steps In Development Of Taste]  
 
* A Science News story that looks at the role of Wnt pathway in the development of taste. "In the present study, the researchers found that in mice in which the actions of Wnt proteins were blocked, taste papilla buds completely failed to develop. Conversely, in mice in which Wnt signaling was over activated, their tongues were covered with many and large papillae and taste buds." It also briefly discusses neural pathways of taste and abnormalities.
 
* A Science News story that looks at the role of Wnt pathway in the development of taste. "In the present study, the researchers found that in mice in which the actions of Wnt proteins were blocked, taste papilla buds completely failed to develop. Conversely, in mice in which Wnt signaling was over activated, their tongues were covered with many and large papillae and taste buds." It also briefly discusses neural pathways of taste and abnormalities.
  
 
+
'''4.''' Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. '''Taste Receptors and the Transduction of Taste Signals'''. Available from: http://www.ncbi.nlm.nih.gov/books/NBK11148/
'''4.'''Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. '''Taste Receptors and the Transduction of Taste Signals'''. Available from: http://www.ncbi.nlm.nih.gov/books/NBK11148/
 
 
* This book chapter covers a variety of transduction mechanisms for taste cells. It is quite detailed, however has some great diagrams to explain the content. The concluding paragraph provides a good summary: "The overall picture that emerges from these admittedly complicated details is that taste cells have a variety of transduction mechanisms. In general, individual taste cells respond to several types of chemical stimuli. Nevertheless, taste cells also exhibit gustatory selectivity. Like olfactory cells, the lower the threshold concentration for detecting a single tastant, the greater the selectivity of the relevant taste cell. Finally, taste receptor mechanisms also adapt to the ongoing presence of a stimulus, although the mechanisms are not understood. If a chemical is left on the tongue for a sufficient time, it ceases to be perceived (consider saliva, for example). Thus, to obtain the full taste of foods, one must either frequently change the types of foods placed in the mouth or wait a sufficient time between helpings, facts that have long been appreciated by restauranteurs and gourmets."
 
* This book chapter covers a variety of transduction mechanisms for taste cells. It is quite detailed, however has some great diagrams to explain the content. The concluding paragraph provides a good summary: "The overall picture that emerges from these admittedly complicated details is that taste cells have a variety of transduction mechanisms. In general, individual taste cells respond to several types of chemical stimuli. Nevertheless, taste cells also exhibit gustatory selectivity. Like olfactory cells, the lower the threshold concentration for detecting a single tastant, the greater the selectivity of the relevant taste cell. Finally, taste receptor mechanisms also adapt to the ongoing presence of a stimulus, although the mechanisms are not understood. If a chemical is left on the tongue for a sufficient time, it ceases to be perceived (consider saliva, for example). Thus, to obtain the full taste of foods, one must either frequently change the types of foods placed in the mouth or wait a sufficient time between helpings, facts that have long been appreciated by restauranteurs and gourmets."
 
  
 
'''5.'''<pubmed>17108952</pubmed>  
 
'''5.'''<pubmed>17108952</pubmed>  
 
* This article describes the receptors and cells involved in the different types of taste (sweet, sour, bitter, salty and umami)
 
* This article describes the receptors and cells involved in the different types of taste (sweet, sour, bitter, salty and umami)
 
  
 
'''6.'''<pubmed>17287575</pubmed>  
 
'''6.'''<pubmed>17287575</pubmed>  
 
* This review focuses on the development of fungiform papillae in rodents
 
* This review focuses on the development of fungiform papillae in rodents
 
  
 
'''7.'''<pubmed>15581865</pubmed>  
 
'''7.'''<pubmed>15581865</pubmed>  

Revision as of 12:28, 22 August 2012

From the Course Coordinator

2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing


--Mark Hill 09:58, 18 September 2012 (EST) This is a recent review on vision. http://jcb.rupress.org/content/190/6/953.full JCB content allows reuse.

http://www.jove.com/video/3730/isolation-and-culture-of-human-fungiform-taste-papillae-cells

--Mark Hill 08:17, 16 August 2012 (EST) This small section at the top of your discussion page allows me to easily distribute information to all students looking at the group discussion page.

Please do not delete, edit or move the template {{Template:2012GroupDiscussion}} from the top of this page.

1. Search:

2. History

  • Embryology History Explore the rich history of sensory research. In particular look through the available images that may complement the text. Any of this material can be used, you should cite the original paper or textbook. Gray | 1921 Bailey and Miller




Natalie - Normal function & abnormal function

Liz - tongue & taste development

Jordan - time line of discoveries

Jared - structure & function; recent findings




Hey guys, Unfortunately a lot of other groups seem to want to do hearing & vision as well, so I thought maybe we should choose to do taste. Let me know what you think!

I also brainstormed a few topic headings... feel free to add to it or change the order around

Headings:

  • Introduction (what is the project about?)
  • Time line of major discoveries / History (early researchers)
  • Structure & Function
  • Tongue development (brief)
  • Taste development - time line and detailed
  • Normal function
  • Abnormal function
  • Current research (recent findings)
  • Glossary and Abbreviations
  • References


--Z3289738 11:42, 15 August 2012 (EST)




Lets do: Sensory - Hearing

From a bit of research this afternoon, I couldn't find much on skin development in terms of "sense organ"/"sense development". I suggest if we do Sensory we do hearing as there was alot of information (inner, middle, outer). And also there are specific screening procedures involved during pregancy.

Couple of link below with basic surface information that we could use as a starting point.

[1]

[2]




Hi guys

Organ = liver

Sensory = vision / skin / hearing

--Z3289738 12:02, 8 August 2012 (EST)

really usefull website including information on phisiology etc [3]

Useful articles

Hi guys, just putting a subheading of interesting articles found:

1. <pubmed>21978088</pubmed>

2. UNSW Embryology Development of Taste

  • This website provides a really great overview of taste developmental timing & overview, tastebuds, receptors, pathways, genes and provides great references for further research - and its a UNSW site!

3. Researchers Discover Initial Steps In Development Of Taste

  • A Science News story that looks at the role of Wnt pathway in the development of taste. "In the present study, the researchers found that in mice in which the actions of Wnt proteins were blocked, taste papilla buds completely failed to develop. Conversely, in mice in which Wnt signaling was over activated, their tongues were covered with many and large papillae and taste buds." It also briefly discusses neural pathways of taste and abnormalities.

4. Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Taste Receptors and the Transduction of Taste Signals. Available from: http://www.ncbi.nlm.nih.gov/books/NBK11148/

  • This book chapter covers a variety of transduction mechanisms for taste cells. It is quite detailed, however has some great diagrams to explain the content. The concluding paragraph provides a good summary: "The overall picture that emerges from these admittedly complicated details is that taste cells have a variety of transduction mechanisms. In general, individual taste cells respond to several types of chemical stimuli. Nevertheless, taste cells also exhibit gustatory selectivity. Like olfactory cells, the lower the threshold concentration for detecting a single tastant, the greater the selectivity of the relevant taste cell. Finally, taste receptor mechanisms also adapt to the ongoing presence of a stimulus, although the mechanisms are not understood. If a chemical is left on the tongue for a sufficient time, it ceases to be perceived (consider saliva, for example). Thus, to obtain the full taste of foods, one must either frequently change the types of foods placed in the mouth or wait a sufficient time between helpings, facts that have long been appreciated by restauranteurs and gourmets."

5.<pubmed>17108952</pubmed>

  • This article describes the receptors and cells involved in the different types of taste (sweet, sour, bitter, salty and umami)

6.<pubmed>17287575</pubmed>

  • This review focuses on the development of fungiform papillae in rodents

7.<pubmed>15581865</pubmed>

  • This article focuses on the role of Sonic hedgehog on tongue and taste papilla development.


--Z3289738 10:44, 22 August 2012 (EST)