Uploads by Z3290270

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Date Name Thumbnail Size Description Versions
09:13, 13 October 2011 Regions of the brain significant in Huntington's disease.jpg (file) 348 KB Coronal view of the brain, showing the main basal ganglia nuclei. The section is angled rostrocaudally to encounter most of the BG nuclei in a single section. '''C''', cortex; '''STR,''' striatum; '''GPe''', globus pallidus pars externa; '''GPi''', globus 1
08:56, 13 October 2011 Key cellular pathogenic mechanisms in Huntington's disease.jpg (file) 47 KB Key cellular pathogenic mechanisms in Huntington's disease (HD). Multiple cellular pathways have been implicated in the pathogenesis of HD. These mechanisms could be exclusive or, more likely, have a high degree of cross-talk. '''A:''' the mutation in hun 1
06:35, 10 October 2011 Regions of the brain.jpg (file) 348 KB Coronal view of the brain, showing the main basal ganglia nuclei. The section is angled rostrocaudally to encounter most of the BG nuclei in a single section. C, cortex; STR, striatum; GPe, globus pallidus pars externa; GPi, globus pallidus pars interna; 1
09:41, 6 October 2011 Huntingtin gene.jpeg (file) 15 KB   1
12:24, 22 September 2011 Inheritance pattern in Huntington's Disease.jpeg (file) 15 KB Huntington's disease is an autosomal dominant disorder. If one parent is affected, the child has a 50% chance of inheriting the mutation on the huntingtin gene on their 4th chromosome. Illustration by: z3290270 Inspiration: Yale Madical group - Yale Sc 1
23:55, 21 September 2011 Healthy Huntingtin protein and Huntingtin gene mutated by Huntington's Disease.jpg (file) 76 KB The Huntingtin protein in an individual not affected by Huntington's disease will have a CAG (cytosine-guanine-adenine)repeat of 10-26. The Huntigntin gene in an individual affected by Huntington's disease is mutated which causes a CAG repeat of 36-121 t 1
06:33, 19 September 2011 Key cellular pathogenic mechanisms in HD.jpg (file) 47 KB Key cellular pathogenic mechanisms in Huntington's disease (HD). Multiple cellular pathways have been implicated in the pathogenesis of HD. These mechanisms could be exclusive or, more likely, have a high degree of cross-talk. A: the mutation in huntingti 1
21:09, 17 August 2011 Establishment of HD hybrid cell line.jpg (file) 93 KB (A) First polar body of mature rhesus macaque oocyte was removed by gentle squeezing through a slit of zona pellucida (A-a). Staining of 1st polar body DNA (arrowhead) and oocyte DNA (arrow) (A-b). HD monkey skin cell was placed under the zona pellucida ( 1