Quicktime Development Animation - Adrenal Medulla

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Adrenal Medulla Development This animation shows the dual embryonic origins of the adrenal development. Adrenal Cortex mesothelium origin, epithelium lining the body cavity at the site of adrenal development Late Fetal Period - differentiates to form cortical zones Birth - zona glomerulosa, zona fasiculata present Year 3 - zona reticularis present Adrenal Medulla neural crest origin, migrate adjacent to coelomic cavity, initially uncapsulated and not surrounded by fetal cortex, cells have neuron-like morphology 2 cell types - secrete epinepherine (adrenaline) 80%; secrete norepinepherine (noradrenaline* 20% Links: Quicktime | Quicktime version | Flash version | Endocrine - Adrenal Development | Endocrine Lecture

Medulla

Neural crest cells migrate toward the coelomic cavity wall and form the adrenal medulla. These chromaffin (chromaphil) cells originally named because of their staining (yellow) with chromium salts.

Cortex

Week 4 celomic epithelium (mesothelium) cells proliferate initially forming small buds that separate from the epithelium.

Week 6 these now mesenchymal cells first form the fetal adrenal cortex which will be later replaced by the adult cortex.

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