Quicktime Aschheim-Zondek Test 1928: Difference between revisions
From Embryology
No edit summary |
No edit summary |
||
Line 11: | Line 11: | ||
** only primordial, preantral and antral follicles present. | ** only primordial, preantral and antral follicles present. | ||
This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus | This early mouse test was later replaced with a similar, but simpler, urine test using either the Frog (Xenopus) or rabbit animal models. | ||
Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG). | Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG). |
Revision as of 13:16, 15 November 2012
width=450px|height=625px|controller=true|autoplay=false</qt> | This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test.
The basis of the original historic Aschheim-Zondek[1] test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice. These changes could be seen by carrying out histology on the mouse ovary to detect follicle development.
This early mouse test was later replaced with a similar, but simpler, urine test using either the Frog (Xenopus) or rabbit animal models. Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG).
Reference |