Quicktime Aschheim-Zondek Test 1928: Difference between revisions
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| valign="top" |This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test. | | valign="top" |This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test. | ||
The basis of the original historic Aschheim-Zondek<ref>Aschheim, S., and Zondek, B., Klin. Wschr., 7 8, 1401 (1928).</ref> test developed in 1928 was to identify the changes in immature female mouse genital system by female human urine injected subcutaneously into these immature mice. | The basis of the original historic Aschheim-Zondek<ref>Aschheim, S., and Zondek, B., Klin. Wschr., 7 8, 1401 (1928).</ref> test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice. | ||
* If the woman was pregnant - the presence of hormones (hCG) induced changes in the mouse genital tract physiologically similar to those produced by sex hormones. | * If the woman was pregnant - the presence of hormones (hCG) induced changes in the mouse genital tract physiologically similar to those produced by sex hormones. | ||
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This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus frog. | This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus frog. | ||
Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG) | |||
Animation based upon original line drawings.<ref><pubmed>20318243</pubmed></ref> | Animation based upon original line drawings.<ref><pubmed>20318243</pubmed></ref> | ||
Revision as of 12:41, 15 November 2012
| width=450px|height=625px|controller=true|autoplay=false</qt> | This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test.
The basis of the original historic Aschheim-Zondek[1] test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice.
This early mouse test was later replaced with a similar, but simpler, urine test using the Xenopus frog. Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG)
Reference |
