Nephron Development Movie

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Embryology - 27 Apr 2024 Expand to Translate
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<html5media height="400" width="500">File:Nephron_development.mp4</html5media>

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Early Renal Development

This animation shows the process of early renal (kidney) development.

Legend

Ureteric Bud - developing ureter, pelvis, calyces, collecting ducts
Metanephric Blastema (intermediate mesoderm) - developing glomeruli, capsule, nephron tubules

Links: MP4 version | Urogenital Sinus Movie | Renal System Development | Movies

Nephron Development

disorganised mesenchymal cells become a highly organised epithelial tubule
Condensation - groups of about 100 cells condense tightly together to form a distinct mass
Epithelialisation - condensed cells lose their mesenchymal character and gain epithelial
At end of this period formed a small epithelial cyst complete with a basement membrane, cell-cell junctions and a defined cellular apico-basal polarity.

Early morphogenesis

cyst invaginates twice to form a comma
then a S-shaped body one invagination site later becomes the glomerular cleft
At about this time blood vessel progenitors invade cleft to begin construction of vascular component of glomerulus
Tubule maturation specialised transporting segments of nephron differentiate complex of convoluted tubules is created

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Cite this page: Hill, M.A. (2024, April 27) Embryology Nephron Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Nephron_Development_Movie

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