Movie - Parental genomes
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Parental_genome_mix_01_icon.jpg</wikiflv> | Movie shows initial parental genomes mixing in early embryonic mitosis.
In the mouse zygote, separation of chromatin according to parental origin is preserved up to the four-cell embryo stage and then gradually disappears. This movie shows that up to the 4 cell stage in the preimplantation embryo, the distribution of the 2 parental genomes remain segregated. After this stage, there is a gradual mixing of the 2 genomes with each cell division.
Image frames kindly provided by Thomas Haaf. |
Reference
<pubmed>10684246</pubmed>
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