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==Trisomy 21 (Down Syndrome) Newborn== | ==Trisomy 21 (Down Syndrome) Newborn== | ||
Down syndrome or [[trisomy 21]] is caused by nondisjunction of chromosome 21 in a parent who is chromosomally normal and is one of the most common chromosomal abnormalities in liveborn children | Down syndrome or [[trisomy 21]] is caused by nondisjunction of chromosome 21 in a parent who is chromosomally normal and is one of the most common chromosomal abnormalities in liveborn children. | ||
The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes. The karyotype is the characteristic chromosome complement as identified by staining and can only be identified during cell division when chromosomes are folded. The chromosomes when organised as an image in sequence are called a karyogram or idiogram. | The frequency of trisomy 21 in the population is approximately 1 in 650 to 1,000 live births, in Australia between 1991-97 there were 2,358 Trisomy 21 (Down) infants. | ||
* The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes. | |||
* The karyotype is the characteristic chromosome complement as identified by staining and can only be identified during cell division when chromosomes are folded. | |||
* The chromosomes when organised as an image in sequence are called a karyogram or idiogram. | |||
Revision as of 16:50, 26 October 2010
Trisomy 21 (Down Syndrome) Newborn
Down syndrome or trisomy 21 is caused by nondisjunction of chromosome 21 in a parent who is chromosomally normal and is one of the most common chromosomal abnormalities in liveborn children.
The frequency of trisomy 21 in the population is approximately 1 in 650 to 1,000 live births, in Australia between 1991-97 there were 2,358 Trisomy 21 (Down) infants.
- The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes.
- The karyotype is the characteristic chromosome complement as identified by staining and can only be identified during cell division when chromosomes are folded.
- The chromosomes when organised as an image in sequence are called a karyogram or idiogram.
Image Source: CDC Dr. Godfrey P. Oakley
UNSW Embryology http://embryology.med.unsw.edu.au/Defect/page21.htm
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