File:Polar body extrusion model.jpg

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Polar Body Extrusion Model

A simplified model depicting the cortical cap protrusion and spindle midzone-induced membrane furrowing during polar body extrusion.

  • A - Chromosomes induce formation of a cortical actomyosin cap/ring prior to polar body extrusion. The squared region of the cortical cap/ring is shown on the top, an actin cap (red) surrounded by a myosin II ring (green).
  • B - Egg activation induces the cortical cap protrusion.
  • C - The anaphase spindle midzone induces unilateral furrowing.
  • D - Spindle rotation.
  • E - Spindle midzone induces bilateral furrowing and abscission of polar body.



Links: Oocyte Development | Meiosis


Reference

<pubmed>21867530</pubmed>| PMC3179692 | Cell Div.


Copyright

© 2011 Wang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Figure 5. 1747-1028-6-17-5-l.jpg http://www.celldiv.com/content/6/1/17/figure/F5


See also

A 4D movie showing the DNA bead-induced ectopic polar body extrusion during meiosis II. The DNA beads (shown in blue) were injected at 10 O'clock position. Microtubules were labeled by microinjection of rhodamine conjugated tubulin. Note that the DNA bead spindle underwent rotation from horizontal to vertical position and the DNA beads were kept in the eggs after ectopic polar body extrusion. Maternal chromosomes are out of the z-sections.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179692/bin/1747-1028-6-17-S1.AVI



Cite this page: Hill, M.A. (2024, April 27) Embryology Polar body extrusion model.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Polar_body_extrusion_model.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current16:07, 18 March 2013Thumbnail for version as of 16:07, 18 March 20131,200 × 435 (70 KB)Z8600021 (talk | contribs)==Polar body extrusion model== A simplified model depicting the cortical cap protrusion and spindle midzone-induced membrane furrowing during polar body extrusion. (A) Chromosomes induce formation of a cortical actomyosin cap/ring prior to polar body...

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