File:Patten1938 plate30.jpg

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Plate 30

1. Usual appearance of the valvula foraminis ovalis as seen from the left in the hart of a newborn infant. Note the fullness of the valvula which is represented in the bulged out position it assmnes when subjected to excess fluid pressure from the right atrium through the foramen ovale. The size and position of the foramen ovale are indicated by the broken line. 2. Resorption of septum primum in an abnormal area dorsal to the usual site of ostium secundum. In this instance the abnormality is of no functional significance since it does not unguard the foramen ovale.
3. Slight incompetence of valvula foraminis ovalis due to excess resorption of septum primtnn at the normal site of ostium secundum. This is a. common condition, occurring in some 20 per cent of newborn infants. It is apparently “corrected” in most cases by postnatal changes either in septum primmn or septum secundum and probably has no functional significance. 4. Incompetence of valvula due to excess resorption at the normal site of ostium secundum combined with resorption at an abnormal site. This defect is definitely more extensive than the apparently correctable type shown in Fig. 3, and xmdoubtedly would persist throughout life.
5. The valvula is abnormally resorbed in two small areas but these defects are so slight that they would be of no significance were they not combined with an abnormally large foramen ovale. The large foramen ovale due to defective development of septum secundum is the condition of primary importance in this case. 6. Extensive defects of the valvula due to over-resorption in the normal and in several abnormal locations.


Patten BM. Developmental defects at the foramen ovale. (1938) Am J Pathol. 14(2):135-162. PMID 19970381

Cite this page: Hill, M.A. (2024, March 4) Embryology Patten1938 plate30.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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