File:Ovarian follicle growth in vitro.jpg

From Embryology

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A comparison of follicular growth in a 2-D vs 3-D culture system

2-D culture system

With 2-D growth granulosa cell migration away from the oocyte is evident with time in culture, leaving the oocyte vulnerable for premature extrusion.

3-D culture system

Pre-antral follicles embedded in hydrogel maintain their 3-D architecture. Granulosa cell expansion occurs in all directions resulting in less stress on gap junctions.

Original file name: Figure 1. 1477-7827-8-119-1-l.jpg

Reference

<pubmed>20946661</pubmed>| Reprod Biol Endocrinol.


© 2010 Desai et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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current10:19, 23 February 2011Thumbnail for version as of 10:19, 23 February 20111,000 × 769 (73 KB)S8600021 (talk | contribs)==A comparison of follicular growth in a 2-D vs 3-D culture system== ===2-D culture system=== With 2-D growth granulosa cell migration away from the oocyte is evident with time in culture, leaving the oocyte vulnerable for premature extrusion. ===3-D

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