From Embryology

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Ovary - Primary Follicle

Histological image showing both primordial follicles and a single primary follicle.

There are several different nomenclatures for the stages of follicle maturation. It probably does not matter which naming system you use, as long as you are consistent and use the same set of terminology for all stages. Early stages of follicle development appear to be gonadotropin (Gn) independent and with development become gonadotropin "sensitive" and then "dependent" . (UK spelling is gonadotrophin).

  • Primordial Follicle - Alternate nomenclature: small follicle or type 1, 2, 3 (25cells)
  • Primary Follicle - Alternate nomenclature: preantral follicle or type 4 (26-100 cells), type 5 (101-300 cells)
  • Secondary Follicle - Alternate nomenclature: small and large antral follicle or type 6 (3001-500 cells), type 7 (501-1000 cells)
  • Preovulatory Follicle - Alternate nomenclature: Graafian follicle or type 8 (>1000 cells)
  • Atresia - At any one time the majority of follicles are destined not to complete maturation and at any stage (from type 4-7) degeneration of the follicle can occur.

Links: Oocyte Development | Ovary Development

Ovary histology: Tunica Albuginea x20 | Tunica albuginea, Germinal epithelium x40 | Primary follicle, primordial follicle, oocyte, x40 | Secondary follicle, cumulus oophorus, zona pelucida, granulosa cells, oocyte x20 | Corpus luteum, theca lutein cells, granulosa lutein cells, Loupe | Corpus luteum, theca lutein cells, granulosa lutein cells, x10 | Corpus luteum, theca lutein cells, granulosa lutein cells, x40 | Corpus albicans, primary follicle, primordial follicle, granulosa cells, oocyte x20 | Menstrual Cycle | Ovary Development

Histology image H&E high power

Links: Histology | Histology Stains | Blue Histology images copyright Lutz Slomianka 1998-2009. The literary and artistic works on the original Blue Histology website may be reproduced, adapted, published and distributed for non-commercial purposes. See also the page Histology Stains.

Cite this page: Hill, M.A. (2024, June 23) Embryology Ova41he.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G


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Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan

current16:32, 6 May 2012Thumbnail for version as of 16:32, 6 May 2012450 × 600 (113 KB)Z8600021 (talk | contribs)
11:17, 28 July 2009Thumbnail for version as of 11:17, 28 July 2009300 × 400 (66 KB)MarkHill (talk | contribs)Ovary Histology Source: UWA Blue Histology