File:Mouse palate increasing p63.jpg
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Molecular consequences of increasing p63 expression during palatal development
(A, B) The expression of Bcl11b (A, B), Znf750 (C, D), Jag2 (E,F) and Perp (G, H), all of which are down-regulated in the medial edge epithelia of wild-type mice, is maintained in the medial edge epithelia of their Krt5-tTA;pTRE-ΔNp63α bi-transgenic littermates. In contrast, Mmp13 which is normally expressed in the midline epithelial seam of wild-type mice as they adhere until degeneration of the seam, is down-regulated in the medial edge epithelia of Krt5-tTA;pTRE-ΔNp63α embryos. p: palatal shelves; t: tongue. Scale bars: 200 μm.
Pgen.1006828.g007.jpg
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 10:52, 22 October 2018 | | 654 × 1,199 (314 KB) | Z8600021 (talk | contribs) | Molecular consequences of increasing p63 expression during palatal development (A, B) The expression of Bcl11b (A, B), Znf750 (C, D), Jag2 (E,F) and Perp (G, H), all of which are down-regulated in the medial edge epithelia of wild-type mice, is mainta... |
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