File:Mouse hypothalamus SHH expression 01.jpg

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Mouse Hypothalamus Sonic hedgehog Expression

Distribution of sonic hedgehog Shh-lineage cells from the different progenitor domains in the mouse adult hypothalamus‎.

(A) Adult mouse brain in sagittal view showing the hypothalamus (shaded gray).

(B, D) Summary of distribution of cells fate-mapped at early and late stages. Magnified view of the shaded area showing the transverse hypothalamic subdivisions and some of the largest nuclei and Shh-lineage progenitor domains in the E12.5 neuroepithelium (small profiles; see also Figure 2). In the schematic of the adult hypothalamus, closed circles indicate neurons, open circles indicate astrocytes, and stars indicate tanycytes.

(C, E) Transverse section through the adult tuberal hypothalamus.

Legend

  • ac, anterior commissure
  • ARH, arcuate nucleus
  • DMH, dorsomedial nucleus
  • LH, lateral hypothalamus
  • LM, lateral mammillary nucleus
  • ME, median eminence
  • MM, medial portion of mammillary body
  • mth, mammillothalamic tract
  • ox, optic chiasm
  • PH, posterior hypothalamus
  • PMD, dorsal premammillary nucleus
  • PMV, ventral premammillary nucleus
  • PVH, paraventricular hypothalamic nucleus
  • SuM, supramammillary nucleus
  • TA, tuberal area
  • VMH, ventromedial nucleus

Reference

Alvarez-Bolado G, Paul FA & Blaess S. (2012). Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions. Neural Dev , 7, 4. PMID: 22264356 DOI.

Copyright

© 2012 Alvarez-Bolado et al.; licensee BioMed Central Ltd

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Figure 8. 1749-8104-7-4-8.jpg

Cite this page: Hill, M.A. (2024, April 27) Embryology Mouse hypothalamus SHH expression 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_hypothalamus_SHH_expression_01.jpg

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