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From Embryology

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Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice

Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminished deltoid tuberosity (*).

Newborn Ktcn-PITX2 mice also exhibit a thickening of the distal humerus, which tends to partly dislocate the radius anteriorly and also slightly dislocate the proximal part of the ulna in a more lateral-dorsal position, which makes the ulna appear twisted (arrows).

Reference

Holmberg et al. BMC Developmental Biology 2008 8:25 doi:10.1186/1471-213X-8-25 BMC Developmental Biology


Copyright

© 2008 Holmberg et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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current20:34, 14 September 2009Thumbnail for version as of 20:34, 14 September 2009600 × 812 (71 KB)S8600021 (talk | contribs)Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice. Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminis

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