File:Mouse eye neural crest.jpg

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Mouse Eye Neural Crest

Neural crest (NC)-derived cells contribute to ocular development.

  • a Toluidine blue staining of an adult eye. The boxed areas correspond to b and c
  • b A detailed view of the corneal assembly, including outer epithelium, stroma, and inner endothelium
  • c The chamber angle at the irido-corneal transition which includes the trabecular meshwork (tm).
  • d-j In vivo fate mapping of NC-derived, β-galactosidase (βGal)-expressing cells (blue)
  • d The NC origin of corneal keratocytes (arrows) and of corneal endothelium (arrowhead).
  • e Structures of the chamber angle, including the trabecular meshwork are seen to be NC-derived.
  • f At E10, the optic cup is surrounded by NC-derived cells expressing βGal.
  • g-i The majority of the cells in the periocular mesenchyme (arrows), which forms the anterior eye segment, are of NC origin, as assessed from E11.5 to E13.5.
  • j The primary vitreous at E13.5 (arrowheads) shows a strong NC contribution.


Links: Image - Mouse eye neural crest | Image - cornea and anterior chamber | Image - cornea | Image - Mouse eye TGF-beta model | Vision - Cornea Development | Vision Development | Neural Crest | Head Development

Reference

<pubmed>16403239</pubmed>| J Biol.


Copyright

© 2005 Ittner et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Ittner et al. Journal of Biology 2005 4:11 doi:10.1186/jbiol29 Original file name: Jbiol29-1.jpg


Cite this page: Hill, M.A. (2024, April 14) Embryology Mouse eye neural crest.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_eye_neural_crest.jpg

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current18:25, 30 August 2011Thumbnail for version as of 18:25, 30 August 20111,086 × 1,509 (483 KB)S8600021 (talk | contribs)
18:20, 30 August 2011Thumbnail for version as of 18:20, 30 August 2011600 × 840 (158 KB)S8600021 (talk | contribs)==Mouse Eye Neural Crest== Neural crest (NC)-derived cells contribute to ocular development. (a) Toluidine blue staining of an adult eye. The boxed areas correspond to b and c (b) a detailed view of the corneal assembly, including outer epithelium, st