File:Mouse eye E18.jpg

Mouse Eye (E18)

Toluidine blue staining of semi-thin sagittal sections of eyes at E18.

Compound ocular anomalies in Tgfbr2-mutant mice. (a) Toluidine blue staining of semi-thin sagittal sections of eyes at E18 reveals a smaller size with no anterior chamber and an infiltration of cells behind the lens in Tgfbr2-mutant embryos as compared with control embryos. Boxes indicate magnified regions shown in the other panels; scale bars represent 250 μm.

• b - corneal stroma
• c - Structures of the forming chamber angle, including the trabecular meshwork (black arrowhead)
• d - primary vitreous consists of loosely arranged vessels of the hyaloid vascular system (arrows).
• e - retina displays typical patterning, with clear separation into an inner layer (IRL) and an outer layer (ORL).

Links: Image - Mouse eye neural crest | Image - cornea and anterior chamber | Image - cornea | Image - Mouse eye TGF-beta model | Vision - Cornea Development | Vision Development | Neural Crest | Head Development

Reference

<pubmed>16403239</pubmed>| J Biol.

Copyright

© 2005 Ittner et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Ittner et al. Journal of Biology 2005 4:11 doi:10.1186/jbiol29

Original file name: Jbiol29-3.jpg Original figure a-e cropped, resized and relabeled.