File:Mouse-neural crest Sox10 E10.5.jpg: Difference between revisions

Mouse E10.5

Neural crest cell distribution by wholemount in situ hybridisation for Sox10 expression at E10.5 in wild-type.

Wild-type and heterozygous embryos showed normal cranial (V, VII/VIII, IX, Xj (jugular) and Xn (nodose)) and dorsal root ganglia (drg). Chuzhoi homozygous mutants exhibit abnormally shaped trigeminal ganglia (V), and apparent fusion of the ninth (IX) and tenth (Xn) cranial ganglia. The distrubution of neural crest cells in the spinal region also appears abnormal, with disturbance of the normal V-shaped arrangement of stained cells in the dorsal root ganglia. B, E, H, K are higher power views of the branchial arches (K is left side of embryo shown in J); C, F, I, L are higher power views of the dorsal root ganglia.

Original file name: Figure Figure 8.A-C (original full image has been cropped, text deleted, label added and size altered)

Note there was no scale bar in the original figure.

Reference

<pubmed>20704721</pubmed>| BMC Dev Biol.

© 2010 Paudyal et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.