File:Molecular endocrine pancreas cells 01.jpg: Difference between revisions
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* similar to alpha cells in that it is dependent on Arx. | * similar to alpha cells in that it is dependent on Arx. | ||
* similar to epsilon cells in that both gastrin and ghrelin are frequently co-expressed with glucagon in the embryonic pancreas. | * similar to epsilon cells in that both gastrin and ghrelin are frequently co-expressed with glucagon in the embryonic pancreas. | ||
:'''Links:''' [[Endocrine - Pancreas Development]] | [[Developmental_Signals_-_Pax|Pax]] | [[Molecular Development]] | |||
{| | {| | ||
! Factor Information | ! Factor Information | ||
|- | |- | ||
| | | valign=top| | ||
* '''Ngn3''' - Neurogenin3 [http://omim.org/entry/604882 OMIM 604882] | * '''Ngn3''' - Neurogenin3 [http://omim.org/entry/604882 OMIM 604882] | ||
** basic helix-loop-helix transcription factor involved in the determination of neural precursor cells in the neuroectoderm. | ** basic helix-loop-helix transcription factor involved in the determination of neural precursor cells in the neuroectoderm. | ||
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* '''NeuroD1''' - Neurogenic Differentiation 1 [http://omim.org/entry/601724 OMIM 601724] | * '''NeuroD1''' - Neurogenic Differentiation 1 [http://omim.org/entry/601724 OMIM 601724] | ||
** a basic helix-loop-helix (bHLH) protein that acts as a transcription factors involved in determining cell type during development. | ** a basic helix-loop-helix (bHLH) protein that acts as a transcription factors involved in determining cell type during development. | ||
| | | valign=top| | ||
* '''Arx''' - Aristaless-Related Homeobox, X-Linked [http://www.omim.org/entry/300382 OMIM 300382] | * '''Arx''' - Aristaless-Related Homeobox, X-Linked [http://www.omim.org/entry/300382 OMIM 300382] | ||
** homeobox protein that belongs to the Aristaless-related subset of the paired (Prd) class of homeodomain proteins. | ** homeobox protein that belongs to the Aristaless-related subset of the paired (Prd) class of homeodomain proteins. | ||
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** transcription factor containing a paired box domain. | ** transcription factor containing a paired box domain. | ||
|} | |} | ||
===References=== | ===References=== | ||
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Journal.pone.0070397.g007.jpg | Journal.pone.0070397.g007.jpg | ||
[[Category:Pancreas]][[Category:Endocrine]][[Category:Molecular]] | [[Category:Pancreas]][[Category:Endocrine]][[Category:Molecular]][[Category:Hox]][[Category:Pax]] | ||
Revision as of 08:11, 31 August 2014
Molecular Development of Endocrine Pancreas Cells
Model placing gastrin cells in the transcriptional hierarchy of endocrine cells in the pancreas.
Pancreatic G cells
- similar to alpha cells in that it is dependent on Arx.
- similar to epsilon cells in that both gastrin and ghrelin are frequently co-expressed with glucagon in the embryonic pancreas.
| Factor Information | |
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References
<pubmed>23940571</pubmed>| PLoS One.
Copyright
© 2013 Suissa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal.pone.0070397.g007.jpg
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| current | 07:41, 31 August 2014 |  | 800 × 804 (71 KB) | Z8600021 (talk | contribs) | endocrine cells in the pancreas. Journal.pone.0070397.g007.jpg Category:PancreasCategory:EndocrineCategory:Molecular |
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