File:Molecular endocrine pancreas cells 01.jpg: Difference between revisions
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* '''Pdx1''' - Pancreas/Duodenum Homeobox Protein 1 [http://omim.org/entry/600733 OMIM 600733] | |||
** transcription (transactivator) factor binds the TAAT element in the promoter region of target genes, mainly those involved in pancreas development. | |||
* '''Ngn3''' - Neurogenin3 [http://omim.org/entry/604882 OMIM 604882] | * '''Ngn3''' - Neurogenin3 [http://omim.org/entry/604882 OMIM 604882] | ||
** basic helix-loop-helix transcription factor involved in the determination of neural precursor cells in the neuroectoderm. | ** basic helix-loop-helix transcription factor involved in the determination of neural precursor cells in the neuroectoderm. |
Revision as of 08:51, 31 August 2014
Molecular Development of Endocrine Pancreas Cells
Model placing gastrin cells in the transcriptional hierarchy of endocrine cells in the pancreas.
Pancreatic G cells
- similar to alpha cells in that it is dependent on Arx.
- similar to epsilon cells in that both gastrin and ghrelin are frequently co-expressed with glucagon in the embryonic pancreas.
- Links: Endocrine ancreas | Pax | Molecular Development
Factor Information | |
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References
<pubmed>23940571</pubmed>| PLoS One.
Copyright
© 2013 Suissa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal.pone.0070397.g007.jpg
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