File:Menstrual cycle.png: Difference between revisions

Human Menstrual Cycle Hormonal Overview

Diagram showing typical hormonal changes during the human menstrual cycle.

• Cycle days are numbered (-14 to +14) with respect to peak (0) of mid-cycle leutenizing hormone surge.
• Cycle days are often numbered (1 to 28) from the first day (1) of menses.
• Ovulation occurs around the time of leutenizing hormone surge mid-cycle.
• There is great variability in human menstrual cycle length.
• There are cycle and hormonal age dependent changes.
• Not shown are the Inhibin A and Inhibin B levels.
• New figure version is more accurate for body temperature and estrogen changes.
• Even more smoothed versions are shown in simplified diagrams.

Legend

• FSH - follicle stimulating hormone (from anterior pituitary)
• GnRH - gonadotrophin releasing hormone (from hypothalamus also called LH-releasing hormone)
• LH - leutenizing hormone (from anterior pituitary)

References

• The pituitary and ovarian hormone curves are based upon Greenspan's Endocrinology, where the actual levels have been measured.
• The body temperature curve is based upon Sex differences and reproductive hormone influences on human odor perception. Doty RL, Cameron EL. Physiol Behav. 2009 May 25;97(2):213-28. Epub 2009 Mar 9. Review. Erratum in: Physiol Behav. 2009 Oct 19;98(4):517. PMID: 19272398
• HPG Axis based upon NIAAA Alcohol’s Effects on Female Reproductive Function, Mary Ann Emanuele, M.D., Frederick Wezeman, Ph.D., and Nicholas V. Emanuele, M.D. Figure 1
• Uterus changes cropped from http://en.wikipedia.org/wiki/File:MenstrualCycle2_en.svg