File:Illustration of Sox signalling pathway.jpg
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Description
The diagram illustrates the signalling pathway taken by the transcription factor Sox10. Firstly, it bind with its partner factor Pouf3f1/2 to form a Sox-pair complex, which activates the Erg2 gene. Erg2 then serves as the second partner factor that bind together with Sox10 to express myelin genes during Schwann cell development.
This image was inspired from the following paper: Kamachi Y & Kondoh H. (2013). Sox proteins: regulators of cell fate specification and differentiation. Development , 140, 4129-44. PMID: 24086078 DOI.
- Note - This image was originally uploaded as part of an undergraduate science student 2018 project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.
Mark Hill (talk) 11:58, 18 October 2018 (AEDT) Description, reference and Student template OK. There is no description of what "1" and "2" is meant to show in the figure. Description could have been more detailed.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 17:39, 15 October 2018 | | 837 × 532 (50 KB) | Z5229431 (talk | contribs) | The diagram illustrates the signalling pathway taken by the transcription factor Sox10 and its partner factor Pouf3f1/2, which activates the Erg2 gene that serves as the second partner factor to express myelin genes during Schwann cell development. |
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