File:Human thymus week6.jpg

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Human Thymus Week 6 Development

Expression profile of known regulators of mouse thymus organogenesis in human thymus development.

Images show whole or sectioned human embryos or microdissected thymic primordia after in situ hybridization with the probes indicated. Ages of embryos or dissected thymus lobes are as shown.

(A-D′) TBX1, HOXA3 and PAX1 images show side view of whole embryos (top) and coronal sections (bottom). PAX9 images show side view of whole embryo; lower panel shows detail of upper panel.

(E,E′) FOXN1 images showing ventral view of whole embryos.

(F-F″) P63 images showing side view of whole embryos (left and middle) and dissected thymic lobe.

(G-H) BMP4 and BMP2 images showing side view of whole embryos.

(I) CLDN4 image showing dissected thymic lobe. Images are representative of at least two independent analyses.

Legend: PP1, first PP; PP2, second PP; PP3, third PP; PP4, fourth PP; Th, thymus; Wk, week.

Embryos mid- to late week 6 (17), GA week 8.

Links: thymus | BMP | HOX | PAX | TBX | Week 6

Reference

Farley AM, Morris LX, Vroegindeweij E, Depreter ML, Vaidya H, Stenhouse FH, Tomlinson SR, Anderson RA, Cupedo T, Cornelissen JJ & Blackburn CC. (2013). Dynamics of thymus organogenesis and colonization in early human development. Development , 140, 2015-26. PMID: 23571219 DOI.


Copyright

© 2013. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

Fig. 2. PMID added to figure, text above modified from figure legend.


Cite this page: Hill, M.A. (2024, April 17) Embryology Human thymus week6.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Human_thymus_week6.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current16:13, 7 September 2018Thumbnail for version as of 16:13, 7 September 20182,000 × 1,941 (400 KB)Z8600021 (talk | contribs)==Morphological features of early human thymus development== Embryos - mid- to late week 6 ({{CS17}}). :'''Links:''' {{Thymus}} ===Reference=== {{#pmid:23571219}} ====Copyright==== © 2013. Published by The Company of Biologists Ltd This is an Op...

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