File:Human fetal membrane 03.jpg

From Embryology

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Human Fetal Membranes - Fatty Acid Amide Hydrolase

Immunohistochemical staining for fatty acid amide hydrolase (FAAH) on human term fetal membranes. Anandamide (AEA) endocannabinoid is degraded to arachidonic acid and ethanolamine by the microsomal enzyme fatty acid amide hydrolase (FAAH).

  • Am - Amnion
  • Ch - chorion
  • Dec - decidua

Bar = 50 µm

Human fetal membrane 01.jpg


<pubmed>19238202</pubmed>| PLoS One.

Citation: El-Talatini MR, Taylor AH, Elson JC, Brown L, Davidson AC, et al. (2009) Localisation and Function of the Endocannabinoid System in the Human Ovary. PLoS ONE 4(2): e4579. doi:10.1371/journal.pone.0004579

Copyright: © 2009 El-Talatini et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Panel cropped, resized and contrast adjusted from Figure 1. Immunohistochemical staining for CB1, CB2, FAAH and NAPE-PLD on control tissues.


Images on the left side of the panel represent the negative control (IgG/serum) and images on the right side of the panel are sections incubated with specific antibodies/antisera. The tissues used in a–f are human fetal membranes whereas g and h are human endometrium. CB1, CB2 and FAAH Immunoreactivity was observed in the amnion (Am), chorion (Ch) and decidua (Dec) of term fetal membranes, whilst NAPE-PLD immunoreactivity was observed mainly in the endometrial glands (Gl) with sparse staining in endometrial stroma (S). The images are representatives from at least six samples and were taken at 200× magnification. Bar = 50 µm.

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current18:01, 6 May 2012Thumbnail for version as of 18:01, 6 May 2012726 × 545 (88 KB)Z8600021 (talk | contribs)==Human Fetal Membranes - Cannabinoid Receptor 2== Immunohistochemical staining for Cannabinoid Receptor 2 (CB2) on human term fetal membranes. * '''Am''' - Amnion * '''Ch''' - chorion * '''Dec''' - decidua Bar = 50 µm Human fetal membrane 01.jpg

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