File:Healthy Huntingtin protein and Huntingtin gene mutated by Huntington's Disease.jpg

From Embryology

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The Huntingtin protein in an individual not affected by Huntington's disease will have a CAG (cytosine-guanine-adenine)repeat of 10-26. The Huntigntin gene in an individual affected by Huntington's disease is mutated which causes a CAG repeat of 36-121 times in the Huntingtin protein. This leads to neurodegenration and the consequent loss of cognitive abilities due to complications created by the expanded polyglutamine tract.

Illsutrated by: z3290270

Inspiration: Illustration by Emily Carlson of National Institute of Medical Sciences, Living with Huntington's. [1]


Reference

http://publications.nigms.nih.gov/findings/sept08/hunting.asp


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Assessment

+ Image relevant to group topic. + Figure meets student drawn criteria for project. Clear and well organised. + Figure legend includes explanation for peer teaching component. + Copyright, citation and student disclaimer included. - Part of the figure base been cropped at the top.



Note - This image was originally uploaded as part of a student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.




Cite this page: Hill, M.A. (2024, June 17) Embryology Healthy Huntingtin protein and Huntingtin gene mutated by Huntington's Disease.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Healthy_Huntingtin_protein_and_Huntingtin_gene_mutated_by_Huntington%27s_Disease.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current23:55, 21 September 2011Thumbnail for version as of 23:55, 21 September 2011945 × 424 (76 KB)Z3290270 (talk | contribs)The Huntingtin protein in an individual not affected by Huntington's disease will have a CAG (cytosine-guanine-adenine)repeat of 10-26. The Huntigntin gene in an individual affected by Huntington's disease is mutated which causes a CAG repeat of 36-121 t

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