File:Hassall1849 plate41 fig10.jpg

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Plate LXI. Fig. 10. Compound cells of thymus

Plate LXI.

Magnified 378 diameters.

original text source for identification of "Hassall's corpuscles" within the thymus.

"The "milky fluid" contained in the follicles and reservoir is made up, to a great extent, of an immense number of granular nuclei, as well as numerous cells of large size, which do not appear hitherto to have been either described or figured in a satisfactory manner, and which are probably to be regarded in the light of parent cells. (See Plate LXI. fig. 10.)
Many of these cells contain several granular nuclei, each of which is surrounded by one or more concentric lamellae ; they thus resemble the cartilage cells found in the inter-vertebral substance, and also certain species of Microcystis, a genus of Fresh-water Algae."

Online Editor - This historic textbook figure is often cited as the original source for "Hassall's corpuscles" within the thymus. Note the reticular cells form an "onion-skin" arrangement of cytoplasmic layers. See also the later historic description of the increase in both number present and size with thymus age by Hammar in early 1900's (Hammar JA. Zur Histogenese und Involution der Thymusdriise. Anat. Anz., 27: 1909 Fiinfzig Jahre Thymusforschung. Ergebn. Anat. Entwickl-gesch. 19: 1-274.)

Original scanned file name - Microscopicanato12hass_orig_0811.jp2


Hassall AH. The microscopic anatomy of the human body, in health and disease. (1849) Samuel Hurley, Fleet Street, London.

Cite this page: Hill, M.A. (2024, April 17) Embryology Hassall1849 plate41 fig10.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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